38570-10-4

Upstream product

• 38436-36-1 (2E)-3-phenyl-2-nitroprop-2-enenitrile 
• 36193-89-2 N-benzylidene-N-(bis-methoxycarbonyl-methyl)-anilinium betaine 
• 113436-48-9 4,5-Diphenyl-4,5-dihydro-[1,2,4]triazole-3,3-dicarboxylic acid dimethyl ester 

Relevant academic research and scientific papers

Thermolyse de nitro-3 pyrrolidines. Obtention de pyrrolines-3 par elimination de HNO2

The cycloaddition of an azomethine ylide to an α-nitro alkene with a single orientation has been carried out and HNO2 has been removed thermally from the resulting 3-nitropyrrolidine according to a radical mechanism giving rise to a 3-pyrroline.Thus α-nitro alkenes behave like potential alkynes.Usually, alkynes give rise to the two possible orientations in 1,3 dipolar cycloadditions.

Cycloadditions dipolaires 1,3 aux derives nitres α ethyleniques, acetyleniques potentiels. I. Reaction avec des ylures d'azomethine. Orientation et stereochimie de la cycloaddition

The stereochemistry of the nitroolefins 1 prepared by known methods was unambigously established.Their reactions with azomethine ylides (e.g. 8) was studied and the stereochemistry of the adducts as well.This preliminary work was necessary to substantiate a discussion of structural (pyrrolidines conformational analysis) and mechanistic problems (dipolarophile-azomethine ylide approach and HNO2 elimination from the nitro pyrrolidines).