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38597-12-5

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  • China Biggest Factory Manufacturer Supply 4-METHYLUMBELLIFERYL-ALPHA-D-GALACTOPYRANOSIDE CAS 38597-12-5

    Cas No: 38597-12-5

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38597-12-5 Usage

Chemical Properties

Off-White Solid

Uses

Different sources of media describe the Uses of 38597-12-5 differently. You can refer to the following data:
1. A fluorogenic substrate in the assay of a-galactosidase
2. A fluorogenic substrate in the assay of α-galactosidase.
3. FFluorescent substrate for ?-galactosidase activity in cell extracts, lysosomes and human blood serum. The lower pKa of the hydrolysis product, allows its detection at phisiological pH5.

Definition

ChEBI: An alpha-D-galactoside having a 4-methylumbelliferyl substituent at the anomeric position

Check Digit Verification of cas no

The CAS Registry Mumber 38597-12-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,8,5,9 and 7 respectively; the second part has 2 digits, 1 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 38597-12:
(7*3)+(6*8)+(5*5)+(4*9)+(3*7)+(2*1)+(1*2)=155
155 % 10 = 5
So 38597-12-5 is a valid CAS Registry Number.

38597-12-5Relevant articles and documents

Based on 4 - methyl [...] synthesis method of a plurality of glycoside

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Paragraph 0082; 0083, (2018/10/11)

The invention discloses a method for synthesizing various glucosides on a basis of 4-methylumbelliferone. According to the invention, a glycosyl donor peracetyl saccharide and a glycosyl acceptor 4-methylumbelliferone are subjected to a glycosylation reaction under room temperature or under heating with dichloromethane or 1,2-dichloroethane as a solvent and with the combined effect of Lewis acid boron trifluoride ethyl ether and organic alkali triethylamine or pyridine; and protecting groups are removed, such that various glucosides based on 4-methylumbelliferone can be obtained. The glucosides include 4-methylumbelliferone-beta-D-glucopyranosiduronide, 4-methylumbelliferone-beta-D-glucopyranoside, 4-methylumbelliferone-beta-D-xylopyranoside, 4-methylumbelliferone-beta-D-ribofuranoside, 4-methylumbelliferone-alpha-D-galactopyranoside, and 4-methylumbelliferone-alpha-D-mannopyranoside. The method is simple, and can produce a beta or alpha single-configuration target. A glycosylation reaction yield can reach 17-93%.

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