Filipin II is a minor component of the filipin complex, a family of pentaene antifungal metabolites first isolated from Streptomyces filipinensis and reported by researchers at Upjohn in 1955. It is structurally characterized by the absence of a hydroxy moiety on the pentyl side chain, making it more hydrophobic and causing it to elute later than filipin III on reverse phase HPLC.
38620-77-8
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Basic information
- Product Name: Filipin II
- Synonyms: (3R,4S,6S,8S,10R,12R,14R,16S,17E,19E,21E,23E,25E,27S,28R)-4,6,8,10,12,14,16,27-Octahydroxy-3-hexyl-17,28-dimethyloxacyclooctacosa-17,19,21,23,25-pentaene-2-one;Filipin II
- CAS NO:38620-77-8
- Molecular Formula: C35H58O10
- Molecular Weight: 638.83
- EINECS: N/A
- Product Categories: N/A
- Mol File: 38620-77-8.mol
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: /
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: N/A
- Solubility: N/A
- CAS DataBase Reference: Filipin II(CAS DataBase Reference)
- NIST Chemistry Reference: Filipin II(38620-77-8)
- EPA Substance Registry System: Filipin II(38620-77-8)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 38620-77-8(Hazardous Substances Data)
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38620-77-8 Usage
Uses
Used in Pharmaceutical Industry:Filipin II is used as a broad-spectrum antifungal agent for its potent activity against various fungi. Its mechanism of action involves binding to cell membrane sterols, which disrupts membrane integrity and inhibits fungal growth.
Used in Antitumor Applications:
Filipin II is used as an antitumor agent due to its ability to exhibit antitumor activities, making it a potential candidate for cancer treatment research.
Used in Antiviral Applications:
Filipin II is used as an antiviral agent, leveraging its capacity to inhibit viral replication and activity, thus offering potential therapeutic benefits in combating viral infections.
Check Digit Verification of cas no
The CAS Registry Mumber 38620-77-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,8,6,2 and 0 respectively; the second part has 2 digits, 7 and 7 respectively.Calculate Digit Verification of CAS Registry Number 38620-77:
(7*3)+(6*8)+(5*6)+(4*2)+(3*0)+(2*7)+(1*7)=128
128 % 10 = 8
So 38620-77-8 is a valid CAS Registry Number.
38620-77-8Upstream product
38620-77-8Downstream Products
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Filipin II
