386210-75-9Relevant academic research and scientific papers
Highly regio- and stereoselective iodohydroxylation of 1,2-allenylic sulfoxides in the presence of benzyl thiol
Wang, Minyan,Fu, Chunling,Ma, Shengming
experimental part, p. 1775 - 1786 (2011/09/13)
The iodohydroxylation of 1,2-allenyl sulfoxides with iodine in the presence of benzyl thiol afforded 3-hydroxy-2-iodo-2(E)-alkenyl sulfides in good yields and high regio- and stereoselectivities. In this reaction it was observed that the sulfoxide functionality was reduced to sulfide and the water in the reaction mixture plays an important role for the stereoselectivity observed. A mechanism involving the attack of benzyl thiol at the positively charged sulfur atom in the five-membered intermediate 2 has been proposed. Copyright
Studies on the regio- and stereoselectivity of halohydroxylation of 1,2-allenyl sulfides or selenides
Ma, Shengming,Hao, Xueshi,Meng, Xiaofeng,Huang, Xian
, p. 5720 - 5724 (2007/10/03)
It was observed that the halohydroxylation of 1,2-allenyl sulfides or selenides with Br2 (CuBr2 or NBS) or I2 and water demonstrated a fairly good regioselectivity (i.e., the C=C bond that is remote from the S or Se atom w
Highly regio- and stereoselective halohydroxylation reaction of 1,2-allenyl phenyl sulfoxides. Reaction scope, mechanism, and the corresponding Pd- or Ni-catalyzed selective coupling reactions
Ma, Shengming,Ren, Hongjun,Wei, Qi
, p. 4817 - 4830 (2007/10/03)
A highly regio- and stereoselective halohydroxylation of 1,2-allenyl sulfoxides with X+ and water was developed. The reaction shows E-stereoselectivity. In the iodohydroxylation reaction, I2 was used to introduce the iodine atom. For
