38624-62-3

Usage

InChI:InChI=1/C6H9ClO2/c1-3-9-6(8)4-5(2)7/h4H,3H2,1-2H3

Upstream product

• 623-73-4 diazoacetic acid ethyl ester 
• 71-55-6 1,1,1-trichloroethane 
• 141-97-9 ethyl acetoacetate 
• 64-17-5 ethanol 
• 6214-28-4 (E)-3-chloro-2-butenoic acid 
• 6213-90-7 (Z)-3-chloro-2-butenoic acid 

Downstream Products

• 35523-67-2 4,7-dihydro-5-methyl-7-oxo[1,2,4]triazolo[1,5-a]pyrimidine 
• 1212-27-7 3-<4-Chlorphenoxy>-crotonsaeureethylester 
• 85852-71-7 2-Methyl-5,6-dihydro-4(H)-oxo-1,3-thiazino<2,3-b>chinazolin 
• 55831-56-6 cis/trans-3-chlorocrotonic acid 
• 1191997-16-6 3-(2-trifluoromethyl-phenoxy)-but-2-enoic acid ethyl ester 
• 1158-30-1 4-Brom-3-(4-butyloxy-phenoxy)-crotonsaeure-ethylester 
• 1838-33-1 4-bromo-3-(2-methoxy-phenoxy)-but-2-enoic acid ethyl ester 
• 1473-56-9 4-Brom-3-<4-chlorphenoxy>-crotonsaeureethylester 
• 1681-80-7 4-Brom-3-p-tolyloxy-crotonsaeureethylester 
• 610-89-9 2-acetyl-pent-4-enoic acid ethyl ester 
• 1215-13-0 3-(2-methoxy-phenoxy)-but-2-enoic acid ethyl ester 
• 1506-69-0 3-(4-Butyloxy-phenoxy)-crotonsaeure-ethylester 
• 1212-26-6 3-p-tolyloxy-crotonic acid ethyl ester 
• 64393-47-1 ethyl 2-acetyl-3-phenyl-4-pentenoate 

Relevant academic research and scientific papers

A New Method for the Preparation of γ,δ-Unsaturated Ketones via Claisen Rearrangement

Thermal rearrangement of monosodium salts of 3-(allyloxy)crotonates derived from primary and secondary allylic alcohols and of disodium salts of 3-(allyloxy)-2-alkenoic acids affords γ,δ-unsaturated ketones.

PYRROLIDINONE GLUCOKINASE ACTIVATORS

Provided herein are compounds of the formula (I): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of metabolic diseases and disorders such as, for example, type II diabetes mellitus.

Synthesis of functionalized 2-alkoxybenzoates, 2-aryloxybenzoates and xanthones based on formal [3+3] cyclocondensations of 3-alkoxy- and 3-aryloxy-1-silyloxy-1,3-butadienes with 3-silyloxy-2-en-1-ones

Functionalized 2-alkoxy- and 2-aryloxybenzoates were prepared by formal [3+3] cyclocondensations of 3-alkoxy- and 3-aryloxy-1-silyloxy-1,3-butadienes with 3-silyloxy-2-en-1-ones. The reaction of 2-aryloxybenzoates with concentrated sulfuric acid resulted in the formation of xanthones.