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Methyl 2,2-difluoropropanoate, a chemical compound with the molecular formula C5H8O2F2, is a clear, colorless, and flammable liquid characterized by a fruity odor. It serves as a versatile building block in the synthesis of pharmaceuticals and agrochemicals, and also functions as a solvent in various industrial applications.

38650-84-9

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38650-84-9 Usage

Uses

Used in Pharmaceutical Synthesis:
Methyl 2,2-difluoropropanoate is utilized as a key intermediate in the production of pharmaceuticals, contributing to the development of new drugs and enhancing the properties of existing ones. Its unique chemical structure allows for the creation of novel compounds with improved efficacy and reduced side effects.
Used in Agrochemical Production:
In the agrochemical industry, Methyl 2,2-difluoropropanoate is employed as a precursor in the synthesis of various pesticides and herbicides. Its incorporation into these products helps to increase their effectiveness in controlling pests and weeds, thereby improving crop yields and quality.
Used as an Industrial Solvent:
Methyl 2,2-difluoropropanoate is used as a solvent in a range of industrial processes, including the manufacturing of paints, coatings, and adhesives. Its ability to dissolve a wide variety of substances makes it a valuable component in the formulation of these products, enhancing their performance and durability.
Safety Considerations:
Due to its flammable nature and potential hazards, it is crucial to handle Methyl 2,2-difluoropropanoate with care during its production, storage, and use. Proper safety measures, such as the use of protective equipment and adherence to safety protocols, should be implemented to minimize risks and ensure the safe utilization of this chemical compound.

Check Digit Verification of cas no

The CAS Registry Mumber 38650-84-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,8,6,5 and 0 respectively; the second part has 2 digits, 8 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 38650-84:
(7*3)+(6*8)+(5*6)+(4*5)+(3*0)+(2*8)+(1*4)=139
139 % 10 = 9
So 38650-84-9 is a valid CAS Registry Number.

38650-84-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name Methyl 2,2-difluoropropanoate

1.2 Other means of identification

Product number -
Other names methyl 2,2-difluoropropionate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:38650-84-9 SDS

38650-84-9Relevant academic research and scientific papers

Α, α-difluoropropionic production of esters

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Paragraph 0098-0100; 0104-0106; 0120-0122, (2016/10/10)

PROBLEM TO BE SOLVED: To provide a practical method of producing α,α-difluoro esters important as pharmaceutical and agricultural chemical intermediates. SOLUTION: The α,α-difluoro esters are produced by reacting α-halogeno-α-fluoro esters with salts or complexes comprising an organic base and hydrogen fluoride. Dehydrohalogenation of side reaction is controlled in the production method. Only α-fluoro-α,β-unsaturated esters of by-products are treated to be brought specifically into a high boiling-point, a boiling point difference gets remarkably large thereby between the α,α-difluoro ester of an objective product and the unsaturated ester of by-product, and a high purity product of the objective product is efficiently obtained by fractional distillation of a simple operation. The method is the practical method of producing the α,α-difluoro esters capable of solving a problem point in a prior technique. COPYRIGHT: (C)2012,JPOandINPIT

Easy access to CF2-containing molecules based on the reaction of 2,2,3,3-tetrafluorooxetane with various nucleophiles

Yamada, Shigeyuki,Kato, Masahiro,Komori, Yudai,Konno, Tsutomu,Ishihara, Takashi

experimental part, p. 5493 - 5502 (2011/08/10)

2,2,3,3-Tetrafluorooxetane reacted easily with organolithium reagents to give 1,1,3-trisubstituted 2,2-difluoropropan-1-ols in good to excellent yields. On the other hand, the reaction with Grignard reagent led to 3-bromo-1,1-disubstituted 2,2-difluoropro

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