386748-08-9

Upstream product

• 877-35-0 2-bromo-1-phenylbutan-1-one 
• 386748-01-2 2-[4-(tert-butyl-dimethyl-silanyloxy)-phenyl]-3-ethyl-1-(4-methoxy-phenyl)-4-phenyl-butane-1,4-dione 

Downstream Products

• 386748-14-7 1-(2-{4-[4-ethyl-2-(4-methoxy-phenyl)-5-phenyl-furan-3-yl]-phenoxy}-ethyl)-piperidine 

Relevant academic research and scientific papers

Furans with basic side chains: Synthesis and biological evaluation of a novel series of antagonists with selectivity for the estrogen receptor alpha

3-Alkyl-2,4,5-triarylfurans with basic side-chain substituents were prepared as ligands for the estrogen receptor. Those analogues having the basic side chain on the C(4) phenol were high-affinity, ERα-selective antagonists.