38693-01-5Relevant academic research and scientific papers
Isomerization of hetaryl analogues of α-benzoins in basic media
Ivonin, Sergey P.,Lapandin, Andrey V.
, p. 3727 - 3735 (2004)
The α → β isomerization of hetaryl analogues of benzoins occurring in basic media on heating is a convenient preparative way to obtain hydroxy-methylcarbonyl-substituted derivatives of π-excessive heterocycles. The reaction is favored by increased catalyst basicity, solvent polarity, and the electron-donor ability of a hetaryl residue. At room temperature, oxidation to hetaryl analogues of benzil becomes dominating.
Isomerization of (het)aryl-benzoins in basic media
Ivonin,Lapandin,Shtamburg
, p. 154 - 160 (2007/10/03)
The α→β isomerization of the hetaryl analogs of unsymmetrical benzoins on heating in basic media is a convenient preparative method for the production of α-hydroxyacyl derivatives of π-excessive heterocycles. The motivating force here for the isomerizatio
