387350-34-7

Basic information

• Product Name: 2-(METHYLSULFONYL)-1-[2-(TRIFLUOROMETHYL)PHENYL]ETHANONE
• Synonyms: 1-[2-(TRIFLUOROMETHYL)BENZOYL]DIMETHYLSULFONE;1-2[-(TRIFLUOROMETHYL)FLUOROPHENYL]-2-(METHYLSULFONYL)ETHANONE;2-(METHYLSULFONYL)-1-[2-(TRIFLUOROMETHYL)PHENYL]ETHANONE;2-(METHYLSULPHONYLACETYL)BENZOTRIFLUORIDE;2-(METHYLSULFONYLACETYL)BENZOTRIFLUORIDE;1-[2-(TRIFLUOROMETHYL)BENZOYL]DIMETHYLSULPHONE;2-(Methylsulphonyl)-2'-(trifluoromethyl)acetophenone;2-[(Methylsulphonyl)acetyl]benzotrifluoride, 2-(Methylsulphonyl)-1-[2-(trifluoromethyl)phenyl]ethan-1-one
• CAS NO: 387350-34-7
• Molecular Formula: C₁₀H₉F₃O₃S
• Molecular Weight: 266.24
• Mol File: 387350-34-7.mol
• Article Data: 0

Chemical Properties

• Melting Point: 61-63°C
• Boiling Point: 412°Cat760mmHg
• Flash Point: 203°C
• Appearance: /
• Density: 1.386g/cm³
• Vapor Pressure: 5.36E-07mmHg at 25°C
• Refractive Index: 1.48
• CAS DataBase Reference: 2-(METHYLSULFONYL)-1-[2-(TRIFLUOROMETHYL)PHENYL]ETHANONE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(METHYLSULFONYL)-1-[2-(TRIFLUOROMETHYL)PHENYL]ETHANONE(387350-34-7)
• EPA Substance Registry System: 2-(METHYLSULFONYL)-1-[2-(TRIFLUOROMETHYL)PHENYL]ETHANONE(387350-34-7)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36/37/39
• Hazardous Substances Data: 387350-34-7(Hazardous Substances Data)

Usage

Description

2-(METHYLSULFONYL)-1-[2-(TRIFLUOROMETHYL)PHENYL]ETHANONE is a chemical compound characterized by the molecular formula C10H9F3O3S. It is a white to off-white solid that serves as a versatile intermediate in the synthesis of pharmaceuticals and agrochemicals. The presence of a trifluoromethyl group enhances the lipophilicity and bioactivity of the compounds it is used to synthesize, while the methylsulfonyl group provides stability and functionality, making it a valuable building block in synthetic organic chemistry.

Uses

Used in Pharmaceutical Industry:
2-(METHYLSULFONYL)-1-[2-(TRIFLUOROMETHYL)PHENYL]ETHANONE is used as an intermediate in the synthesis of various pharmaceuticals for its ability to increase the lipophilicity and bioactivity of the final products, leading to improved drug efficacy and pharmacokinetics.
Used in Agrochemical Industry:
In the agrochemical industry, 2-(METHYLSULFONYL)-1-[2-(TRIFLUOROMETHYL)PHENYL]ETHANONE is utilized as an intermediate in the synthesis of agrochemicals, contributing to the development of more effective and targeted pesticides and other agricultural chemicals.
Used as a Reagent in Organic Synthesis:
2-(METHYLSULFONYL)-1-[2-(TRIFLUOROMETHYL)PHENYL]ETHANONE is used as a reagent in organic synthesis, taking advantage of its functional groups to facilitate various chemical reactions and the formation of desired products.
Used as a Building Block in Organic Synthesis:
2-(METHYLSULFONYL)-1-[2-(TRIFLUOROMETHYL)PHENYL]ETHANONE is also used as a building block in organic synthesis, providing a stable and functional foundation for the construction of more complex organic molecules with specific properties and applications.

InChI:InChI=1/C10H9F3O3S/c1-17(15,16)6-9(14)7-4-2-3-5-8(7)10(11,12)13/h2-5H,6H2,1H3