38767-34-9

Upstream product

• 4922-98-9 3-Amino-5-phenyl-4H-1,2,4-triazole 

Downstream Products

• 22250-25-5 3-phenyl-5-[N'-(5-phenyl-1H-[1,2,4]triazol-3-yl)-hydrazino]-[1,2,4]thiadiazole 
• 22350-82-9 3-phenyl-5-(5-phenyl-1H-[1,2,4]triazol-3-ylazo)-[1,2,4]thiadiazole 

Relevant academic research and scientific papers

METHODS OF TREATMENT WITH AMINOLEVULINIC ACID SYNTHASE 2 (ALAS2) MODULATORS

Described herein is a compound of Formula I or a pharmaceutically acceptable salt thereof: wherein Ring A R1, R2, a, b, and n are as defined herein. Also described is a method of treating a subject having a disorder in need of treatment, comprising inhibiting aminolevulinic acid synthase 2 (ALAS2) in the subject by administering a compound of Formula (I) or a pharmaceutically acceptable salt thereof. Disorders that are of particular interest are blood disorders, such as porphyria and anemia.