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Usage

Uses

Used in Pharmaceutical Industry:
(3E)-3-(2-furylmethylene)-5-methylfuran-2(3H)-one is used as an intermediate in the synthesis of various pharmaceuticals for its ability to contribute to the development of new drugs with potential therapeutic applications.
Used in Agrochemical Industry:
(3E)-3-(2-furylmethylene)-5-methylfuran-2(3H)-one is used as a precursor in the production of agrochemicals, playing a role in the creation of substances that can help protect crops and enhance agricultural productivity.
Used in Flavor and Fragrance Industry:
(3E)-3-(2-furylmethylene)-5-methylfuran-2(3H)-one is used as a component in the flavor and fragrance industry due to its aromatic properties, contributing to the creation of unique scents and tastes in various consumer products.
Used in Organic Synthesis:
As a building block in organic synthesis, (3E)-3-(2-furylmethylene)-5-methylfuran-2(3H)-one is used to construct more complex molecules, which can have a wide range of applications across different industries, showcasing its versatility and importance in chemical research and development.

Upstream product

• 98-01-1 furfural 
• 591-12-8 5-methyl-2-furanone 

Relevant academic research and scientific papers

Substituted Butanolides and Butenolides: XVII. Substituted 3-(Furan-2-ylmethylidene)furan-2(3H)-ones and 3-(Furan-2-ylmethylidene)dihydrofuran-2(3H)-ones

A number of furan-2-ylmethylidene-substituted lactones were synthesized by condensation of 5-alkylfuran-2(3H)-ones and 4-alkyldihydrofuran-2(3H)-ones with 5-substituted furan-2-carbaldehydes. The reactivity of furan-2(3H)-ones was higher than that of furan-2(5H)-ones due to formation of intermediate conjugated anion. The condensation of 4-alkyldihydrofuran-2(3H)-ones with furan-2-carbaldehydes required more severe conditions than the condensation with furan-2(3H)-ones. The substituent in the furan ring affects the reaction time and yield.

Synthesis of Diesel and Jet Fuel Range Alkanes with Furfural and Angelica Lactone

A route was developed for the synthesis of diesel and jet fuel range C9 and C10 alkanes with furfural and angelica lactone, which can be obtained from hemicellulose and cellulose. It was found that angelica lactone is more reactive than levulinic acid or its other derivates in the aldol condensation with furfural. Among the investigated catalysts, Mn2O3 was found to be the most active and was very stable for the aldol condensation of furfural and angelica lactone. Over Mn2O3, a high carbon yield of C10 oxygenates (about 96%) can be achieved by the aldol condensation of furfural and angelica lactone under mild conditions (353 K, 4 h). By the hydrogenation and hydrodeoxygenation of the aldol condensation product over the Pd/C and Pd-FeOx/SiO2 catalysts, high carbon yields (～96%) of C9 and C10 alkanes were obtained.