387876-60-0Relevant academic research and scientific papers
GPR14 ANTAGONIST
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, (2008/06/13)
A novel GPR14 antagonist. The GPR14 antagonist comprises a compound represented by the formula (I) or a salt thereof wherein Ar represents optionally substituted aryl; X represents a spacer; n is an integer of 1 to 10; R represents an optionally substitut
Preventives and remedies for central nervous system diseases
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, (2008/06/13)
A prophylactic or therapeutic agent for central nervous system diseases based on amyloid β40 secretion inhibitory activity of a compound having urotensin II receptor antagonistic activity or a salt thereof.
USE OF POLYPEPTIDE
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, (2008/06/13)
The present invention provides uses of a polypeptide having a ligand activity to a sensory epithelium neuropeptide-like receptor (SENR) which is a G protein-coupled receptor protein, and a DNA encoding the same. More specifically, the present invention provides an anti-attention-deficit-disorder or anti-narcolepsy agent, which comprises a polypeptide having a ligand activity for SENR or a salt thereof, as well as a method for screening compounds having an anti-attention-deficit-disorder or anti-narcolepsy activity or compounds having an anti-anxiety, anti-depression, anti-insomnia, anti-schizophrenia or anti-fear activity or salts thereof, which comprises using the above polypeptide or a precursor protein of the polypeptide or a salt thereof.
