388-11-4 Usage
Uses
Used in Pharmaceutical Industry:
2-Acetamido-1-nitro-3,5,6-trifluorobenzene is used as a key intermediate in the synthesis of various pharmaceutical compounds. Its unique structure, including the nitro and trifluoro groups, allows for versatile reactivity in chemical reactions, facilitating the creation of diverse medicinal molecules.
Used in Agrochemical Industry:
In the agrochemical sector, 2-Acetamido-1-nitro-3,5,6-trifluorobenzene serves as an essential intermediate for the production of herbicides and insecticides. Its reactivity and stability contribute to the development of effective crop protection agents.
Used in Dye Production:
2-Acetamido-1-nitro-3,5,6-trifluorobenzene is also utilized as an intermediate in the manufacturing of dyes. Its distinct chemical properties enable the production of dyes with specific characteristics, such as color intensity and stability.
It is crucial to handle 2-Acetamido-1-nitro-3,5,6-trifluorobenzene with care due to its potential health hazards and environmental risks. Proper safety measures should be implemented during its production, use, and disposal to minimize any adverse effects.
Check Digit Verification of cas no
The CAS Registry Mumber 388-11-4 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 3,8 and 8 respectively; the second part has 2 digits, 1 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 388-11:
(5*3)+(4*8)+(3*8)+(2*1)+(1*1)=74
74 % 10 = 4
So 388-11-4 is a valid CAS Registry Number.
InChI:InChI=1/C8H5F3N2O3/c1-3(14)12-7-5(10)2-4(9)6(11)8(7)13(15)16/h2H,1H3,(H,12,14)
388-11-4Relevant academic research and scientific papers
TRANSGLUTAMINASE 2 (TG2) INHIBITORS
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, (2020/03/02)
Described herein are compounds and pharmaceutical compositions containing such compounds which inhibit transglutaminase 2 (TG2). Also described herein are methods for using such TG2 inhibitors, alone or in combination with other compounds, for treating diseases or conditions that would benefit from TG2 inhibition.
Identification of metabolites of the tryptase inhibitor CRA-9249: Observation of a metabolite derived from an unexpected hydroxylation pathway
Yu, Walter,Dener, Jeffrey M.,Dickman, Daniel A.,Grothaus, Paul,Ling, Yun,Liu, Liang,Havel, Chris,Malesky, Kimberly,Mahajan, Tania,O'Brian, Colin,Shelton, Emma J.,Sperandio, David,Tong, Zhiwei,Yee, Robert,Mordenti, Joyce J.
, p. 4053 - 4058 (2007/10/03)
The metabolites of the tryptase inhibitor CRA-9249 were identified after exposure to liver microsomes. CRA-9249 was found to be degraded rapidly in liver microsomes from rabbit, dog, cynomolgus monkey, and human, and less rapidly in microsomes from rat. T
