388076-99-1Relevant academic research and scientific papers
Derivatives of (2R,3R,4S)-2-aminomethylpyrrolidine-3,4-diol are selective α-mannosidase inhibitors
Popowycz, Florence,Gerber-Lemaire, Sandrine,Demange, Raynald,Rodriguez-Garcia, Eliazar,Asenjo, Ana Teresa Carmona,Robina, Inmaculada,Vogel, Pierre
, p. 2489 - 2493 (2007/10/03)
A collection of (2R,3R,4S)-3,4-dihydroxypyrrolidin-2-yl derivatives have been tested for their inhibitory activities toward 25 glycosidases. Competitive (Ki = 7.4 μM) and selective inhibition of α-mannosidase from jack bean has been found for (
