388112-72-9Relevant academic research and scientific papers
Pyrrole derivatives
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, (2008/06/13)
Disclosed are novel pyrrole derivatives, a process for their manufacture, pharmaceutical compositions containing such compounds and the use of such compounds in the treatment of HIV mediated diseases.
Arylthiopyridylmethylisopropylpyrrole carbinols, novel NNRTIs endowed with potent anti-HIV-1 activity
Di Santo, Roberto,Costi, Roberta,Artico, Marino,Ragno, Rino,Massa, Silvio,La Colla, Massimiliano,Loddo, Roberta,La Colla, Paolo,Pani, Alessandra
, p. 153 - 167 (2007/10/03)
Pyrrole analogues of the NNRTI S-1153 were synthesized and tested as anti-HIV-1 agents. Among test compounds 5-(3,5-dichlorophenylthio)-4-isopropyl-1-(4-pyridylmethyl)-1H-pyrrole-3- methanol was the most active in cell-based assays against HIV-1 wt and K1
