3882-98-2

Basic information

• Product Name: 2-Amino-2-thiazoline hydrochloride
• Synonyms: 2-AMINO-2-THIAZOLINE HYDROCHLORIDE 98%;4,5-dihydrothiazol-2-amine hydrochloride;4,5-Dihydrothiazol-2-amine monohydrochloride;2-amino-1,3-thiazoline monohydrochloride;2-AMINO-2-THIAZOLINE HYDROCHLORIDE;2-AMINOTHIAZOLE HYDROCHLORIDE;2-AMINOTHIAZOLINE HYDROCHLORIDE;2-AMINOTHIAZOLE HCL
• CAS NO: 3882-98-2
• Molecular Formula: C₃H₇N₂S*Cl
• Molecular Weight: 138.62
• EINECS: 223-416-6
• Product Categories: Thiazole series;Thiazole;Thiophene&Benzothiophene;Heterocyclic Compounds;Building Blocks;Heterocyclic Building Blocks;Thiazolines/Thiazolidines
• Mol File: 3882-98-2.mol
• Article Data: 1

Chemical Properties

• Melting Point: 200-202 °C(lit.)
• Boiling Point: 269.9 °C at 760 mmHg
• Flash Point: 117.1 °C
• Appearance: Cream colored crystalline solid
• Vapor Pressure: 0.105mmHg at 25°C
• Water Solubility: >=10 g/100 mL at 24 ºC
• CAS DataBase Reference: 2-Amino-2-thiazoline hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Amino-2-thiazoline hydrochloride(3882-98-2)
• EPA Substance Registry System: 2-Amino-2-thiazoline hydrochloride(3882-98-2)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 3882-98-2(Hazardous Substances Data)

Usage

Air & Water Reactions

Soluble in water.

Reactivity Profile

Acidic salt of an amine. Materials in this group are generally soluble in water. The resulting solutions contain moderate concentrations of hydrogen ions and have pH's of less than 7.0. They react as acids to neutralize bases. These neutralizations generate heat, but less or far less than is generated by neutralization of inorganic acids, inorganic oxoacids, and carboxylic acid. They usually do not react as either oxidizing agents or reducing agents but such behavior is not impossible. Many of these compounds catalyze organic reactions.

Fire Hazard

Flash point data for 2-Amino-2-thiazoline hydrochloride are not available. 2-Amino-2-thiazoline hydrochloride is probably combustible.

InChI:InChI=1/C3H6N2S.ClH/c4-3-5-1-2-6-3;/h1-2H2,(H2,4,5);1H

Upstream product

• 870-24-6 2-chloroethanamine hydrochloride 
• 17356-08-0 thiourea 

Downstream Products

• 29558-46-1 7-phenyl-2,3-dihydro-thiazolo[3,2-a]pyrimidin-5-one 
• 102862-40-8 2-Chloro-N-(4,5-dihydro-thiazol-2-yl)-2-phenyl-acetamide 
• 5036-02-2 Tetramisole 
• 6558-33-4 N-thiazolinephenylacetamide 
• 6558-36-7 benzoyl amino-2-Δ²-thiazoline 
• 101575-72-8 benzyl-(3-benzyl-thiazolidin-2-ylidene)-amine 
• 131535-08-5 2-diphenoxyphosphoryliminothiazolidine 
• 131534-81-1 2-diphenoxythiophosphoryliminothiazolidine 
• 102862-43-1 2-Chloro-N-(4,5-dihydro-thiazol-2-yl)-2-(4-nitro-phenyl)-acetamide 
• 102862-41-9 2-Chloro-2-(4-chloro-phenyl)-N-(4,5-dihydro-thiazol-2-yl)-acetamide 
• 29558-44-9 6-phenyl-2,3-dihydro-thiazolo[3,2-a]pyrimidin-7-one 
• 29558-43-8 6-phenyl-2,3-dihydro-5H-thiazolo[3,2-a]pyrimidin-5-one 
• 102862-42-0 2-Chloro-N-(4,5-dihydro-thiazol-2-yl)-2-p-tolyl-acetamide 

Relevant articles and documents

Preparation method of tetraimidazole hydrochloride

The invention provides a preparation method of tetraimidazole hydrochloride, which comprises the following steps: preparing tetraimidazole; the preparation method comprises the following step: reacting tetraimidazole, 1, 2-dibromoethyl benzene and 2-aminothiazoline hydrochloride to generate tetraimidazole. The synthetic route is shorter, the comprehensive yield is higher than that of other processroutes, styrene is used as an initiator, tetra-imidazole free alkali is used as a final product, the yield of the hydroxysalt process route is about 65%, the yield of the N (2chloroethyl) alpha (chloromethyl) benzylamine hydrochloride process route is about 72%, and the yield can reach 85% or above when the patent route is used. Meanwhile, the problem of large amount of waste water and waste saltgenerated by multi-step reactions such as chlorination, hydrolysis and cyclization is avoided, the investment of reaction equipment such as an autoclave is avoided, the green chemical engineering requirement is met, the economic benefit is remarkable, and the industrial prospect is good.