38824-44-1

Basic information

• Product Name: 2-phenyl-5,6,7,8-tetrahydro-1H-benzo[f]indole
• Synonyms: 1H-Benz[f]indole, 5,6,7,8-tetrahydro-2-phenyl-
• CAS NO: 38824-44-1
• Molecular Formula: C₁₈H₁₇N
• Molecular Weight: 247.3343
• Mol File: 38824-44-1.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 470.3°C at 760 mmHg
• Flash Point: 210.6°C
• Density: 1.155g/cm³
• Vapor Pressure: 1.45E-08mmHg at 25°C
• Refractive Index: 1.669
• CAS DataBase Reference: 2-phenyl-5,6,7,8-tetrahydro-1H-benzo[f]indole(CAS DataBase Reference)
• NIST Chemistry Reference: 2-phenyl-5,6,7,8-tetrahydro-1H-benzo[f]indole(38824-44-1)
• EPA Substance Registry System: 2-phenyl-5,6,7,8-tetrahydro-1H-benzo[f]indole(38824-44-1)

Safety Data

• Hazardous Substances Data: 38824-44-1(Hazardous Substances Data)

Relevant articles and documents

Chemistry of aminophenols. Part 1: Remarkable additive effect on Sonogashira cross-coupling of 2-carboxamidoaryl triflates and application to novel synthesis of indoles

A novel and general synthesis of indoles has been established by utilizing 2-aminophenols as the starting materials. The key step is a modified Pd(0)-Cu(I)-catalyzed cross-coupling of 1-alkynes with 2-carboxamidoaryl triflates in the presence of n-Bu4NI as the additive. The 2-alkynylanilides obtained were subjected to an alkoxide-mediated cyclization to provide a number of indole containing compounds possessing substituents at the C2, C4, C5, and/or C6 position(s) in good overall yields.