3884-02-4 Usage
Uses
Used in Pharmaceutical Research and Development:
L-Histidine, N-[N-[N-[(phenylmethoxy)carbonyl]glycyl]glycyl]-, methyl ester is used as a building block in the synthesis of peptide compounds for pharmaceutical research and development. Its unique structure allows for the creation of novel peptide-based drugs with potential therapeutic applications.
Used in Peptide Chemistry:
In the field of peptide chemistry, L-Histidine, N-[N-[N-[(phenylmethoxy)carbonyl]glycyl]glycyl]-, methyl ester serves as a key component in the synthesis of complex peptide structures. Its presence in these structures can influence the properties and functions of the resulting peptides, making it a valuable tool for researchers.
Used in Drug Design:
L-Histidine, N-[N-[N-[(phenylmethoxy)carbonyl]glycyl]glycyl]-, methyl ester is utilized in drug design to create new pharmaceutical agents with specific therapeutic targets. Its incorporation into drug molecules can enhance their efficacy, selectivity, and stability, leading to improved treatment options for various diseases and conditions.
Used in the Synthesis of Bioactive Peptides:
In the development of bioactive peptides, L-Histidine, N-[N-[N-[(phenylmethoxy)carbonyl]glycyl]glycyl]-, methyl ester is employed as a starting material or intermediate in the synthesis process. The resulting bioactive peptides may have potential applications in various industries, such as agriculture, food, and cosmetics, due to their antimicrobial, antioxidant, or other beneficial properties.
Used in the Development of Diagnostic Agents:
L-Histidine, N-[N-[N-[(phenylmethoxy)carbonyl]glycyl]glycyl]-, methyl ester may also be used in the development of diagnostic agents, such as imaging agents or biosensors. Its unique chemical properties can be exploited to create compounds that selectively bind to specific biological targets, enabling the detection and monitoring of various diseases and conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 3884-02-4 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,8,8 and 4 respectively; the second part has 2 digits, 0 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 3884-02:
(6*3)+(5*8)+(4*8)+(3*4)+(2*0)+(1*2)=104
104 % 10 = 4
So 3884-02-4 is a valid CAS Registry Number.
3884-02-4Relevant academic research and scientific papers
Synthesis and antitumor properties of an anthraquinone bisubstituted by the copper chelating peptide Gly-Gly-L-His
Morier-Teissier,Boitte,Helbecque,Bernier,Pommery,Duvalet,Fournier,Hecquet,Catteau,Henichart
, p. 2084 - 2090 (2007/10/02)
A new molecule 4 [(GGH-DAE)2DHQ] associating the 1,4,5,8- tetrahydroxyanthraquinone ring (DHQ) of the antitumor drug mitoxantrone (2), two diaminoethylene chains (DAE), and the metal-chelating peptide Gly-Gly- His (GGH) has been synthesized. Such a molecule presents characteristics able to induce antitumor activity: compound 4 intercalates into DNA as measured by ΔT(m), fluorescence quenching, and viscometry; ESR studies demonstrate that several types of Cu complexes are formed depending on pH; and the production of free radicals, as evidenced by spin-trapping, is enhanced by 4. In vitro, in leukemia cells L1210 and mammary cells MCF7, 4 is slightly less cytostatic than mitoxantrone, but substantially less toxic. In vivo, in leukemia P388 on mice, a T/C value of 230 is obtained at 25 mg/kg, higher than the one of mitoxantrone, which is toxic at the same dose.
