1-(5,8,9,10-tetrahydro-6H-[1,3]dioxolo[4,5-h]pyrrolo[2,1-b][3]benzazepin-11-yl)propane-1,2-dione is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.
38848-24-7
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Basic information
- Product Name: 1-(5,8,9,10-tetrahydro-6H-[1,3]dioxolo[4,5-h]pyrrolo[2,1-b][3]benzazepin-11-yl)propane-1,2-dione
- Synonyms:
- CAS NO:38848-24-7
- Molecular Formula: C17H17NO4
- Molecular Weight: 299.3212
- EINECS: N/A
- Product Categories: N/A
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Chemical Properties
- Melting Point: N/A
- Boiling Point: 482.5°C at 760 mmHg
- Flash Point: 245.6°C
- Appearance: N/A
- Density: 1.36g/cm3
- Vapor Pressure: 1.82E-09mmHg at 25°C
- Refractive Index: 1.638
- Storage Temp.: N/A
- Solubility: N/A
- CAS DataBase Reference: 1-(5,8,9,10-tetrahydro-6H-[1,3]dioxolo[4,5-h]pyrrolo[2,1-b][3]benzazepin-11-yl)propane-1,2-dione(CAS DataBase Reference)
- NIST Chemistry Reference: 1-(5,8,9,10-tetrahydro-6H-[1,3]dioxolo[4,5-h]pyrrolo[2,1-b][3]benzazepin-11-yl)propane-1,2-dione(38848-24-7)
- EPA Substance Registry System: 1-(5,8,9,10-tetrahydro-6H-[1,3]dioxolo[4,5-h]pyrrolo[2,1-b][3]benzazepin-11-yl)propane-1,2-dione(38848-24-7)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 38848-24-7(Hazardous Substances Data)
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38848-24-7 Usage
Type of Compound
Chemical compoundStructure
Complex and lengthyTarget Enzyme
Cyclic nucleotide phosphodiesterase 5 (PDE5)Enzyme Function
Regulates levels of cyclic guanosine monophosphate (cGMP) in various tissues and organsMechanism of Action
Inhibits PDE5, increasing cGMP levelsPotential Therapeutic Applications
a. Erectile dysfunctionb. Pulmonary arterial hypertension
c. Cardiovascular disorders
d. Neurological disorders
Chemical Structure
Unique and interesting for further research and drug developmentCurrent Status
Novel and potent inhibitor of PDE5, under investigation for various therapeutic applicationsCheck Digit Verification of cas no
The CAS Registry Mumber 38848-24-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,8,8,4 and 8 respectively; the second part has 2 digits, 2 and 4 respectively.Calculate Digit Verification of CAS Registry Number 38848-24:
(7*3)+(6*8)+(5*8)+(4*4)+(3*8)+(2*2)+(1*4)=157
157 % 10 = 7
So 38848-24-7 is a valid CAS Registry Number.
38848-24-7Upstream product
- 127-17-3 2-oxo-propionic acid
- 35667-11-9 5,8,9,10-tetrahydro-6H-1,3-dioxolo<4,5-h>pyrrolo<2,1-b><3>benzazepine
- 38847-95-9 1-(benzo[1,3]dioxol-5-yl-acetyl)-pyrrolidine-2-carbaldehyde
- 38847-96-0 5,8,9,10-tetrahydro-[1,3]dioxolo[4',5':4,5]benzo[d]pyrrolo[1,2-a]azepin-6-one
- 38848-22-5 2-acetoxy-1-(5,8,9,10-tetrahydro-6H-[1,3]dioxolo[4',5':4,5]benzo[1,2-d]pyrrolo[1,2-a]azepin-11-yl)-propan-1-one
- 38848-23-6 2-hydroxy-1-(5,8,9,10-tetrahydro-6H-[1,3]dioxolo[4',5':4,5]benzo[1,2-d]pyrrolo[1,2-a]azepin-11-yl)-propan-1-one
38848-24-7Downstream Products
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1-(5,8,9,10-tetrahydro-6H-[1,3]dioxolo[4,5-h]pyrrolo[2,1-b][3]benzazepin-11-yl)propane-1,2-dione
