388567-20-2

Upstream product

• 617-86-7 triethylsilane 
• 175084-15-8 [(1,10-phenanthroline)Pd(CH₃)(NC(3,5-C₆H₃(CF₃)2)][B(3,5-C₆H₃(CF₃)2)4] 

Relevant academic research and scientific papers

Mechanism of palladium-catalyzed diene cyclization/hydrosilylation: Direct observation of intramolecular carbometalation

The results of kinetic, deuterium-labeling, and low-temperature NMR studies have established a mechanism for the palladium-catalyzed cyclization/hydrosilylation of dimethyl diallylmalonate (1) with triethylsilane involving rapid, irreversible conversion of the palladium silyl complex [(phen)Pd(SiEt3)(NCAr)]+ [BAr4]- [Ar = 3,5-C6H3(CF3)2] (4b) and 1 to the palladium 5-hexenyl chelate complex {(phen)Pd[η1,η 2-CH(CH2SiEt3)CH2C(CO 2Me)2CH2CH=CH2]}+ [BAr4]- (5), followed by intramolecular carbometalation of 5 to form the palladium cyclopentylmethyl complex trans-{(phen)Pd[CH 2CHCH2C(CO2Me)2CH 2CHCH2SiEt3]-(NCAr)}+ [BAr 4]- (6), and associative silylation of 6 to release 3 and regenerate 4b.

Direct observation of the conversion of a palladium 5-hexenyl chelate complex to a palladium cyclopentylmethyl complex

Warming a solution of {(phen)Pd[η1:η2-CH(CH2SiEt3) CH2C(CO2Me)2CH2CH= CH2]}+[BAr4]- (4) at -41 °C led to first-order decay (κ = (4.7 ± 0.3) × 10-4 M s-1, ΔG? = 17.1 ± 0.1 kcal mol-1) with formation of the palladium cyclopentylmethyl complex {(phen)Pd-[CH2 CHCH2CC(CO2Me)2CH2CHCH2 SiEt3](NC Ar)}+-[BAr4]- (5) in 96 ± 10% yield (1H NMR).