388570-41-0

Basic information

• Product Name: 5-Isoxazolecarbonitrile, 4,5-dihydro-3-[3-methoxy-4-(phenylmethoxy)phenyl]-
• CAS NO: 388570-41-0
• Molecular Formula: C18H16N2O3
• Molecular Weight: 308.337
• Mol File: 388570-41-0.mol

Chemical Properties

• CAS DataBase Reference: 5-Isoxazolecarbonitrile, 4,5-dihydro-3-[3-methoxy-4-(phenylmethoxy)phenyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Isoxazolecarbonitrile, 4,5-dihydro-3-[3-methoxy-4-(phenylmethoxy)phenyl]-(388570-41-0)
• EPA Substance Registry System: 5-Isoxazolecarbonitrile, 4,5-dihydro-3-[3-methoxy-4-(phenylmethoxy)phenyl]-(388570-41-0)

Safety Data

• Hazardous Substances Data: 388570-41-0(Hazardous Substances Data)

Upstream product

• 107-13-1 acrylonitrile 
• 81259-54-3 4-benzyloxy-3-methoxybenzaldehyde oxime 
• 2426-87-1 3-methoxy-4-(phenylmethoxy)benzaldehyde 
• 121-33-5 vanillin 

Relevant articles and documents

Synthesis of new 4,5-dihydroisoxazoles with potential anti-inflammatory activity

This paper reports the synthesis of different 4,5-dihydroisoxazoles which may present anti-inflammatory activity. The methodology employed was based on the 1,3-dipolar cycloaddition of nitrile oxide derived from vanillin to unsaturated compounds. It was u

A simple and efficient method for the synthesis of nitrile oxide from aldoxime using trichloroisocyanuric acid

Treatment of the aldoxime derived from vanilin with trichloroisocyanuric acid in the presence of olefins as dipolarophiles caused the formation of nitrile oxides and subsequent 1,3-dipolar cycloaddition forming the corresponding isoxazoline derivatives in good yields.