388574-59-2

Upstream product

• 4857-06-1 2-chloro-1H-benzoimidazole 
• 106-42-3 para-xylene 
• 104-82-5 4-Methylbenzyl chloride 

Downstream Products

• 1186430-49-8 C₂₅H₃₂N₄O₂ 
• 388575-13-1 [10-(4-methyl-benzyl)-3,4-dioxo-3,4-dihydro-10H-benzo[4,5]imidazo[2,1-c][1,2,4]triazin-2-yl]-acetic acid ethyl ester 
• 388574-96-7 10-(4-methyl-benzyl)-2,10-dihydro-benzo[4,5]imidazo[2,1-c][1,2,4]triazine-3,4-dione 
• 388574-80-9 [1-(4-methyl-benzyl)-1H-benzoimidazol-2-yl]-hydrazine 

Relevant academic research and scientific papers

Metal-free, highly efficient organocatalytic amination of benzylic C-H bonds

A new synthetic approach toward direct C-N bond formation through sp 3 C-H activation has been developed under metal-free conditions. Both primary and secondary benzylic C-H substrates could react smoothly with various amines to give only mono-amination products with good to excellent yields. The Royal Society of Chemistry 2013.

5-HT3R binding of lerisetron: An interdisciplinary approach to drug-receptor interactions

The design, synthesis, and use of lerisetron-based molecular probes to investigate the 5-HT3R binding site are described. A SAR study, which involved distance and electronic parameter modifications of lerisetron's N-benzyl group, resulted in the discovery of a partial agonist.

[1,2,4]Triazino[4,3-a]benzimidazole acetic acid derivatives: A new class of selective aldose reductase inhibitors

Acetic acid derivatives of [1,2,4]triazino[4,3-a]benzimidazole (TBI) were synthesized and tested in vitro and in vivo as a novel class of aldose reductase (ALR2) inhibitors. Compound 3, (10-benzyl[1,2,4]triazino[4,3-a]benzimidazol-3,4(10H)-dion-2-yl)aceti