388574-68-3

Upstream product

• 4857-06-1 2-chloro-1H-benzoimidazole 
• 76283-09-5 4-bromo-2-fluorobenzyl bromide 

Downstream Products

• 388575-19-7 [10-(4-bromo-2-fluoro-benzyl)-3,4-dioxo-3,4-dihydro-10H-benzo[4,5]imidazo[2,1-c][1,2,4]triazin-2-yl]-acetic acid ethyl ester 
• 388575-08-4 10-(4-bromo-2-fluoro-benzyl)-2,10-dihydro-benzo[4,5]imidazo[2,1-c][1,2,4]triazine-3,4-dione 
• 388574-88-7 [1-(4-bromo-2-fluoro-benzyl)-1H-benzoimidazol-2-yl]-hydrazine 

Relevant academic research and scientific papers

[1,2,4]Triazino[4,3-a]benzimidazole acetic acid derivatives: A new class of selective aldose reductase inhibitors

Acetic acid derivatives of [1,2,4]triazino[4,3-a]benzimidazole (TBI) were synthesized and tested in vitro and in vivo as a novel class of aldose reductase (ALR2) inhibitors. Compound 3, (10-benzyl[1,2,4]triazino[4,3-a]benzimidazol-3,4(10H)-dion-2-yl)aceti