388575-86-8Relevant academic research and scientific papers
Exploring the readthrough of nonsense mutations by non-acidic Ataluren analogues selected by ligand-based virtual screening
Pibiri, Ivana,Lentini, Laura,Tutone, Marco,Melfi, Raffaella,Pace, Andrea,Di Leonardo, Aldo
, p. 429 - 435 (2016)
Ataluren, also known as PTC124, is a 5-(fluorophenyl)-1,2,4-oxadiazolyl-benzoic acid suggested to suppress nonsense mutations by readthrough of premature stop codons in the mRNA. Potential interaction of PTC124 with mRNA has been recently studied by molec
