388582-46-5

Upstream product

• 2859-88-3 7-hydroxy-2-methyl-3-phenyl-chromen-4-one 
• 388582-43-2 (2-methyl-3-phenylchromonyl-7)-2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-β-D-glucopyranoside 

Downstream Products

• 388582-52-3 (R)-2-[(4aR,6S,7R,8R,8aS)-7-Acetylamino-2,2-dimethyl-6-(2-methyl-4-oxo-3-phenyl-4H-chromen-7-yloxy)-hexahydro-pyrano[3,2-d][1,3]dioxin-8-yloxy]-propionic acid 
• 388582-49-8 (2-methyl-3-phenylchromonyl-7)-2-acetamido-2-deoxy-4,6-O-isopropylidene-β-D-glucopyranoside 

Relevant academic research and scientific papers

Synthesis of N-acetylglucosaminides with coumarin and chromone aglycones

β-O-Glycosides of N-acetylglucosamine with substituted 7-hydroxychromones and 7-hydroxycoumarins as the aglycones are synthesized. The phenyl hydroxyls' are O-glycosylated in a solid - liquid system with crown-ether catalysts. The structures of the chromone and coumarin N-acetylglucosaminides and their per-O-acetates are proved by PMR spectroscopy.

Synthesis of glycosides of a muramoyldipeptide with chromone aglycones

The synthesis of β-(2-methyl-3-phenylchromonyl-7)- and β-[2-methyl-3-(3,4-trimethylenedioxy) phenylchromonyl-7]glycosides of the methyl ester of N-acetylmuramoyl-L-alanyl-D-isoglutamine, new derivatives of a muramoyldipeptide with chromone aglycones, is described. The starting arylglycosides of N-acetylglucosamine are prepared by glycosylation of 7-hydroxychromone derivatives with the peracetate of α-glucosamine chloride catalyzed by a crown ether. The synthesized β-aryl-4,6-O-isopropylidene-N-acetylmuramic acids are condensed with the dipeptide and deprotected to give the desired glycopeptides.