388593-48-4

Upstream product

• 3879-79-6 (2R,3R,4S,5S,6S)-3,4,5-tris(benzyloxy)-2-((benzyloxy)methyl)-6-methoxytetrahydro-2H-pyran 
• 389085-56-7 Acetic acid (2R,3R,4R,5R)-6-allyl-3,4,5-tris-benzyloxy-tetrahydro-pyran-2-ylmethyl ester 

Downstream Products

• 223122-56-3 (2R,3R,4R,5R,6R)-2-Allyl-6-azidomethyl-3,4,5-tris-benzyloxy-tetrahydro-pyran 
• 223122-93-8 Octadecanoic acid ((2R,3R,4R,5R,6R)-6-allyl-3,4,5-tris-benzyloxy-tetrahydro-pyran-2-ylmethyl)-amide 
• 223123-14-6 Octadecanoic acid [(2R,3R,4R,5R,6R)-3,4,5-tris-benzyloxy-6-(2-oxo-ethyl)-tetrahydro-pyran-2-ylmethyl]-amide 
• 223122-85-8 N-((2R,3R,4R,5R,6R)-6-Allyl-3,4,5-tris-benzyloxy-tetrahydro-pyran-2-ylmethyl)-3-phenyl-propionamide 
• 223123-06-6 3-Phenyl-N-[(2R,3R,4R,5R,6R)-3,4,5-tris-benzyloxy-6-(2-oxo-ethyl)-tetrahydro-pyran-2-ylmethyl]-propionamide 
• 223122-75-6 N-((2R,3R,4R,5R,6R)-6-Allyl-3,4,5-tris-benzyloxy-tetrahydro-pyran-2-ylmethyl)-acetamide 
• 223123-00-0 N-[(2R,3R,4R,5R,6R)-3,4,5-Tris-benzyloxy-6-(2-oxo-ethyl)-tetrahydro-pyran-2-ylmethyl]-acetamide 
• 223122-66-5 C-((2R,3R,4R,5R,6R)-6-Allyl-3,4,5-tris-benzyloxy-tetrahydro-pyran-2-yl)-methylamine 

Relevant academic research and scientific papers

Synthesis of sialyl Lewis x mimetics as selectin inhibitors by enzymatic aldol condensation reactions

Several D-mannosyl phosphate/phosphonate derivatives have been enzymatically prepared as sialyl Lewis x tetrasaccharide mimics, which showed strong-to-moderate inhibition against E-, P-, and L-selectins. The synthesis of these mimics is very straightforward; mannosyl aldehyde derivatives are condensed with dihydroxyacetone phosphate (DHAP) in the presence of a DHAP-dependent aldolase to provide mannosyl phosphates. Copyright (C) 1999 Elsevier Science Ltd.