388605-69-4

Upstream product

• 104-87-0 4-methyl-benzaldehyde 
• 106-47-8 4-chloro-aniline 
• 68-11-1 mercaptoacetic acid 

Downstream Products

• 1627745-58-7 (Z)-2-(4-methylphenyl)-3-(4-chlorophenyl)-5-(4-methylphenylmethylene)-4-thiazolidinone 
• 1627745-57-6 (Z)-2-(4-methylphenyl)-3-(4-chlorophenyl)-5-phenylmethylene-4-thiazolidinone 
• 1627745-59-8 (Z)-2-(4-methylphenyl)-3-(4-chlorophenyl)-5-(4-isopropylphenylmethylene)-4-thiazolidinone 
• 1627745-70-3 3′′-(4-chlorophenyl)-4′-(4-isopropylphenyl)-2′′-(4-methylphenyl)-1′-methyldispiro[indole-3,2′-pyrrolidine-3′,5′′-[1,3]thiazolane]-2(1H),4′′-dione 
• 1627745-69-0 3′′-(4-chlorophenyl)-2′′,4-di(4-methylphenyl)-1′-methyldispiro[indole-3,2′-pyrrolidine-3,5′′-[1,3]thiazolane]-2(1H),4′′-dione 
• 1627745-68-9 3′′-(4-chlorophenyl)-2′′-(4-methylphenyl)-4′-phenyl-1′-methyldispiro[indole-3,2′-pyrrolidine-3′,5′′-[1,3]thiazolane]-2(1H),4′′-dione 

Relevant academic research and scientific papers

One-pot rapid synthesis of thiazole-substituted pyrazolyl-4-thiazolidinones mediated by diisopropylethylammonium acetate

A convenient one-pot, rapid and scalable synthetic protocol has been developed for recently reported anti-inflammatory agents, thiazole-substituted pyrazolyl-4-thiazolidinones. Quantitative multicomponent cyclocondensation of 3-(4-methyl-2-substituted thi

Pd nanoparticles: an efficient catalyst for the solvent-free synthesis of 2,3-disubstituted-4-thiazolidinones

Abstract: Palladium nanoparticles (Pd NPs: ~5-nm diameter) catalysed an efficient, solvent-free protocol for the cyclocondensation reaction of the aldehydes, anilines and mercaptoacetic acid has been developed. This method offers a rapid, relatively economical and ecofriendly protocol for the synthesis of 2,3-disubstituted-4-thiazolidinones for the first time. Moreover, the catalyst can also be easily recovered and recycled with no loss of catalytic activity. Graphical Abstract: [Figure not available: see fulltext.]

A facile synthesis of dispiro[indole-3,2′-pyrrolidine-3,5″-[1, 3]thiazolane] derivatives from 2,3,5-trisubstituted-4-thiazolidinones via 1,3-dipolar cycloaddition reaction

A series of 2″,3″,4′-triaryl-1′- methyldispiro[indole-3,2′-pyrrolidine-3′,5″-[1,3]thiazolane] -2(1H),4″-dione derivatives were successfully synthesised via a three-component 1,3-dipolar cycloaddition reaction of 2,3,5-trisubstituted-4- thiazolidinones, is

Ionic liquid mediated and promoted eco-friendly preparation of thiazolidinone and pyrimidine nucleoside-thiazolidinone hybrids and their antiparasitic activities

Without any catalyst, 2,3-disubstituted-1,3-thiazolidin-4-one derivatives were synthesized efficiently via the three-component reaction of aldehyde, amine and mercaptoacetic acid in [bmim][PF6]. The whole procedure is simple and straightforward