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Usage

Uses

Used in Pharmaceutical Applications:
2H-1,2,3-Triazole-4,5-dicarboxamide(9CI) is utilized as an antitumor agent for its potential to inhibit the growth of cancer cells. It has been studied for its effectiveness in combating various types of cancer, making it a promising candidate for further research and development in oncology.
Used in Agricultural Applications:
In the agricultural industry, 2H-1,2,3-Triazole-4,5-dicarboxamide(9CI) is employed as an antimicrobial agent. Its potential as a fungicide and bactericide has been investigated, with the aim of protecting crops from various microbial infections and diseases, thereby enhancing crop yield and quality.

Upstream product

• 57613-19-1 5-cyano-2H-[1,2,3]triazole-4-carboxylic acid amide 

Relevant academic research and scientific papers

Novel 2H-1,2,3-Triazole sodium complex from N-[2-amino-1,2-dicyanovinyl]alkanamides

Diazotization at 0 °C of N-[2-amino-1,2-dicyanovinyl]ethanamide 2a or propanamide 2b prepared from diaminomaleonitrile (DAMN) 1 using aqueous acetic acid and NaNO2 solution furnished sodium complex 3. The X-ray structure of the complex 3 showed that it is a 1:1 mixture of the neutral 2H-triazole heterocycle 4ii and its anion deprotonated at the central (N) atom of the ring, together with a sodium counter ion and two coordinated water molecules. However, when the diazotization reaction was carried out in the presence of aqueous HCl, the product was 5-cyano-2H-[1,2,3]triazole-4-carboxylic acid amide monohydrate 4ii. Diazotization of DAMN 1 using aqueous HCl furnished 1H-1,2,3-triazole-4,5-dicarbonitrile 5, whereas with acetic acid there was no reaction, and hence no route analogous to that leading to complex 3. The structure of both complex 3 and the triazole monohydrate 4ii were solved using X-ray crystallography, and the compounds under study were fully characterized using spectroscopic techniques.