38869-24-8

Usage

Uses

Used in Pharmaceutical Industry:
Cesium propionate is used as a pharmaceutical intermediate for the synthesis of various drugs and pharmaceutical compounds. Its unique properties make it a valuable component in the development of new medications.
Used in Organic Chemistry:
Cesium propionate is used as an epoxide cleavage and inversion reagent in organic chemistry. It is particularly useful in the synthesis of complex organic molecules, where it can facilitate the cleavage of epoxide rings and the inversion of stereochemistry.

InChI:InChI=1/C3H6O2.Cs/c1-2-3(4)5;/h2H2,1H3,(H,4,5);/q;+1/p-1

Upstream product

• 802294-64-0 propionic acid 

Downstream Products

• 123076-63-1 (4R,5R)-N-<(S)-1-phenylethyl>-4-hydroxy-5-<(propionyloxy)methyl>pyrrolidin-2-one 
• 131373-23-4 DL-6-O-Benzyl-1,2:3,4-di-O-cyclohexylidene-5-O-propionyl-neo-inositol 
• 99612-72-3 Benzoic acid (7S,7aR)-7-propionyloxy-5,6,7,7a-tetrahydro-3H-pyrrolizin-1-ylmethyl ester 
• 87201-63-6 3-{4-[4,5-Dimethoxy-2-((2S,4S,9aS)-2-propionyloxy-octahydro-quinolizin-4-yl)-phenoxy]-phenyl}-propionic acid methyl ester 
• 97389-96-3 benzyl 3-azido-2,3,6-trideoxy-4-O-propionyl-α-L-threo-hex-2-enopyranoside 
• 90754-11-3 1-O-propyonyl-3,4,6-tri-O-benzyl-2,5-anhydro-L-iditol 
• 90754-10-2 2,3,4,6-tetra-O-benzyl-1-O-propionyl-5-O-mesyl-D-glucitol 
• 380883-55-6 3,5-di-O-benzyl-1-O-methyl-2-O-propanoyl-β-D-[2-2H1]ribofuranose 
• 372176-97-1 1-O-methyl-3,5-di-O-benzyl-2-O-propionyl-β-D-ribofuranose-2,3,4,5,5'-2H5 
• 1219141-61-3 C₃₉H₄₇⁽²⁾HN₂O₉Si 
• 1005482-74-5 6-N-benzoyl-9-[2'-O-tert-butyldimethylsilyl-5'-O-(4,4'-dimethoxytrityl)-3'-O-propionyl-xylofuranosyl]adenine 

Relevant academic research and scientific papers

Benzoxazepine-2-one compounds and their use

Disclosed is a squalene synthetase inhibitor which comprises the compound represented by the formula (I) STR1 wherein R1 stands for H or an optionally substituted hydrocarbon group; R2 and R3 independently stand for H, an optionally substituted alkyl group, an optionally substituted phenyl group or an optionally substituted aromatic heterocyclic group; Z stands for a carbon chain containing a double bond or --Z'--C(OH)-- (Z' stands for a bond or a straight-chain or branched alkylene chain); the symbol ......... stands for a double bond or a single bond; Y stands for an optionally esterified carboxyl group, an optionally substituted carbamoyl group, an optionally substituted hydroxyl group, an optionally substituted amino group or an optionally substituted heterocyclic radical having a protonizable hydrogen; X stands for O or S; G stands for O or S; and the ring A is optionally substituted, or a pharmaceutically acceptable salt thereof, and which is useful for the prophylaxis or therapy of hypercholesteremia or coronary sclerosis of mammals.

Optically active compound, liquid crystal composition containing said compound, and liquid crystal optical modulator using said composition

There are disclosed an optically active compound represented by the general formula: STR1 wherein n, R1, R2, R3, R4, Q1, Q2, Q3, and M are defined as in the detailed explanation,

THE FORMATION OF 3,4,6-TRI-O-BENZYL-2,5-ANHYDRO-L-IDITOL FROM 2,3,4,6-TETRA-O-BENZYL-D-GLUCOPYRANOSE. INTRAMOLECULAR DISPLACEMENT OF A SECONDARY MESYLOXY GROUP BY A BENZYLOXY GROUP, IN THE PRESENCE OF CESIUM PROPIONATE

The reaction between 2,3,4,6-tetra-O-benzyl-1,5-di-O-mesyl-D-glucitol and cesium propionate in dimethylformamide at 100 deg C leads to an almost quantitative conversion into 3,4,6-tri-O-benzyl-1-O-propionyl-2,5-anhydro-L-iditol.Closure of the anhydro ring appears to entail anchimeric assistance by the 2-O-benzyl substituent in an SN2 displacement at C-5, leading to an inversion at the latter position.Probable contributors to the marked regio- and stereoselectivity observed for the reaction are a unique property of cesium propionate as compared with other carboxylate salts, large differences in rate between competing reactions, and a geometry highly favorable to an intramolecular displacement process.Conformational properties of 2,5-anhydro-L-iditol, as well as of isomeric 2,5-anhydro-D-mannitol, are described, based on nmr evidence.