38869-91-9

Basic information

• Product Name: pentylurea
• Synonyms: pentylurea;1-Pentylurea;N-Amylurea
• CAS NO: 38869-91-9
• Molecular Formula: C₆H₁₄N₂O
• Molecular Weight: 130.18816
• EINECS: 254-168-7
• Mol File: 38869-91-9.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 200.1°Cat760mmHg
• Flash Point: 74.8°C
• Appearance: /
• Density: 0.948g/cm³
• Vapor Pressure: 0.331mmHg at 25°C
• Refractive Index: 1.451
• CAS DataBase Reference: pentylurea(CAS DataBase Reference)
• NIST Chemistry Reference: pentylurea(38869-91-9)
• EPA Substance Registry System: pentylurea(38869-91-9)

Safety Data

• Hazardous Substances Data: 38869-91-9(Hazardous Substances Data)

Usage

InChI:InChI=1/C6H14N2O/c1-2-3-4-5-8-6(7)9/h2-5H2,1H3,(H3,7,8,9)

Upstream product

• 32847-48-6 pentyl cyanamide 
• 143-33-9 sodium cyanide 
• 110-58-7 n-Pentylamine 
• 590-28-3 potassium cyanate 
• 3954-13-0 pentylisocyanate 
• 917-61-3 sodium isocyanate 
• 556-89-8 nitrourea 
• 684-93-5 1-methyl-1-nitrosourea 
• 506-68-3 bromocyane 

Downstream Products

• 92033-14-2 3-Benzoyl-1-n-pentylharnstoff 
• 15517-31-4 5,5-diethyl-1-pentyl-barbituric acid 

Relevant articles and documents

Ammonium Chloride-Promoted Rapid Synthesis of Monosubstituted Ureas under Microwave Irradiation

Monosubstituted ureas are important scaffolds in organic chemistry. They appear in various biologically active compounds and serve as versatile precursors in synthesis. Monosubstituted ureas were originally prepared using toxic and hazardous phosgene equivalents. Modern methods include transamidation of urea and nucleophilic addition to cyanate salts, both of which suffer from a narrow substrate scope due to the need for a strong acid and prolonged reaction times. We hereby report that ammonium chloride can promote the reaction between amines and potassium cyanate to generate monosubstituted ureas in water. This method proceeds rapidly under microwave irradiation and tolerates a broad range of functional groups. Unlike previous strategies, it is compatible with other nucleophiles, acid-labile moieties, and most of the common protecting groups. The products precipitate out of solution, allowing facile isolation without column chromatography.

OXIDATIVE CYANATION OF AMINYL RADICALS IN SODIUM PEROXYDISULFATE - SODIUM CYANIDE SYSTEM

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Some Extensions of von Braun (BrCN) Reaction on Organic Bases: Part II

Extensions of von Braun Cyanogen bromide reaction on Ephedra alkaloids and simpler bases have resulted in synthesis of substituted oxazolidines and a whole series of nitrogen analogues of ephedrine, desoxy ephedrine and simpler amines.The general applicability and limitations of such extension of the reaction are also discussed. - Key words: von Braun Cyanogen Bromide Reaction