38876-62-9Relevant articles and documents
In silico design, synthesis, and screening of novel deoxyhypusine synthase inhibitors targeting HIV-1 replication
Schroeder, Marcus,Kolodzik, Adrian,Pfaff, Katharina,Priyadarshini, Poornima,Krepstakies, Marcel,Hauber, Joachim,Rarey, Matthias,Meier, Chris
, p. 940 - 952 (2014/05/20)
The human enzyme deoxyhypusine synthase (DHS) is an important host cell factor that participates in the post-translational hypusine modification of eukaryotic initiation factor 5A (eIF-5A). Hypusine-modified eIF-5A plays a role in a number of diseases, in