38877-21-3Relevant academic research and scientific papers
A dihydro maltol and dihydro ethyl maltol synthetic method
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Paragraph 0027; 0028; 0029; 0030, (2017/08/25)
The invention discloses a dihydro maltol and dihydro ethyl maltol synthesis method. The method includes A, according to a formula II, allowing 2-methyl-5, 6-dihydro-2H-pyran and hydrogen peroxide to perform dihydroxylation under the effect of strong acid ion exchange resin, and obtaining a 2-methyl-3 and 4-dihydro-tetrahydropyrane intermediates of a formula III; B, according to the formula III, oxidizing the 2-methyl-3 and 4-dihydro-tetrahydropyrane intermediates through oxidation agent, and obtaining a compound of a formula IV. When R = ethyl, the compound of the formula IV is dihydro ethyl maltol; when R = methyl, the compound of the formula IV is dihydro maltol. The method adopts conventional chemical raw materials, and the reaction condition is mild.
