389062-84-4

Usage

Chemical structure

A diazepine compound with two benzyl groups attached to the nitrogen atoms

Classification

Benzodiazepine derivative

Field of application

Medicinal chemistry for the development of new pharmaceutical drugs

Known properties

Sedative and anxiolytic (anti-anxiety) effects

Common use

Central nervous system depressants

Potential applications

Treatment of anxiety disorders, insomnia, and other conditions related to the central nervous system

Research status

Further research and clinical trials are needed to fully understand its therapeutic potential and safety profile

Upstream product

• 96-21-9 1,3-dibromo-2-hydroxypropane 
• 140-28-3 N,N'-Dibenzylethylenediamine 

Downstream Products

• 459417-40-4 di-tert-butyl 6-oxo-1,4-diazepane-1,4-dicarboxylate 
• 956317-40-1 tert-butyl 6-hydroxy-1,4-diazepane-1-carboxylate 
• 123187-94-0 6-fluoro-1H-1,4-diazepine 
• 1012784-40-5 1,4-dibenzyl-6-fluoroperhydro-1,4-diazepine 
• 28795-81-5 6-hydroxyhexahydro-1H-1,4-diazepine 

Relevant academic research and scientific papers

CXCR2 ANTAGONIST

A compound as a CXCR2 antagonist and an application thereof in preparing a drug as a CXCR2 antagonist. In particular, the present invention relates to a compound represented by formula (II) or an isomer or pharmaceutically acceptable salt thereof.

CARBOXAMIDES AS UBIQUITIN-SPECIFIC PROTEASE INHIBITORS

The present disclosure relates to modulators, such as inhibitors, of at least one pathway chosen from USP28 and USP25, pharmaceutical compositions comprising the inhibitors, and methods of using the inhibitors. The modulators, such as inhibitors, of at least one pathway chosen from USP28 and USP25 can be useful in the treatment of cancers, among other ailments.

AZEPANE DERIVATIVES AND METHODS OF TREATING HEPATITIS B INFECTIONS

Provided herein are compounds useful for the treatment of HBV infection in a subject in need thereof, pharmaceutical compositions thereof, and methods of inhibiting, suppressing, or preventing HBV infection in the subject.

AZEPANE DERIVATIVES AND METHODS OF TREATING HEPATITIS B INFECTIONS

Provided herein are compounds useful for the treatment of HBV infection in a subject in need thereof, pharmaceutical compositions thereof, and methods of inhibiting, suppressing, or preventing HBV infection in the subject.

AZEPANE DERIVATIVES AND METHODS OF TREATING HEPATITIS B INFECTIONS

Provided herein are compounds useful for the treatment of HBV infection in a subject in need thereof, pharmaceutical compositions thereof, and methods of inhibiting, suppressing, or preventing HBV infection in the subject.

Heterocyclic compounds, which are inhibitors of the enzyme DPP-IV

The present invention relates to therapeutically active and selective inhibitors of the enzyme DPP-IV, pharmaceutical compositions comprising the compounds and the use of such compounds for and the manufacture of medicaments for treating diseases that are