389131-91-3Relevant academic research and scientific papers
An intramolecular [2 + 3] cycloaddition route to fused 5-heterosubstituted tetrazoles
Demko, Zachary P.,Sharpless, K. Barry
, p. 4091 - 4094 (2007/10/03)
(matrix presented) Fused 5-heterotetrazole ring systems are synthesized in high yield via intramolecular [2 + 3] cycloadditions of organic azides and heteroatom-substituted nitriles. Cyanates, thiocyanates, and cyanamides are all competent dipolarophiles for this reaction. A variety of scaffolds are tolerated when the new enclosed ring is five- or six-membered.
