38927-32-1 Usage
General Description
1-pentofuranosyl-5-thiocyanatopyrimidine-2,4(1H,3H)-dione is a chemical compound with a complex molecular structure. It contains a pentofuranosyl group, a thiocyanate group, and a pyrimidine-2,4(1H,3H)-dione group. 1-pentofuranosyl-5-thiocyanatopyrimidine-2,4(1H,3H)-dione also contains a five-membered heterocyclic ring formed by four carbon atoms and one oxygen atom, known as furan, which is attached to a pentose sugar. The thiocyanate group adds a sulfur atom and a nitrogen atom to the molecule, while the pyrimidine-2,4(1H,3H)-dione group contributes to the overall pharmacological activity of the compound. This chemical may have potential applications in various fields, including pharmaceuticals, biotechnology, and materials science, due to its unique and intricate structure.
Check Digit Verification of cas no
The CAS Registry Mumber 38927-32-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,8,9,2 and 7 respectively; the second part has 2 digits, 3 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 38927-32:
(7*3)+(6*8)+(5*9)+(4*2)+(3*7)+(2*3)+(1*2)=151
151 % 10 = 1
So 38927-32-1 is a valid CAS Registry Number.
38927-32-1Relevant articles and documents
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Nagamachi et al.
, p. 1025 (1972)
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Synthesis, chemistry, and biological activity of 5 thiocyanatopyrimidine nucleosides as potential masked thiols
Nagamachi,Fourrey,Torrence,Waters,Witkop
, p. 403 - 406 (2007/10/09)
The reaction of chlorothiocyanogen (ClSCN) with various derivatives of uracil was investigated as potential route to 5 mercaptouracils. Reaction of 1,3 dimethyluracil, 1 (β D ribofuranosyl)uracil, 1 (2' deoxy β D ribofuranosyl)uracil, 1 (β D arabinofuranosyl)uracil, 1 (2',3',5' tri O chloroacetyl β D ribofuranosyl)uracil, and 1 (2',3',5' tri O acetyl β D ribofuranosyl)uracil with ClSCN in acetic acid gave the corresponding 5 thiocyanato derivatives in fair to excellent yields. These 5 thiocyanatopyrimidine nucleosides can be reduced by dithiothreitol, sodium dithionite 2 mercaptoethanol, or glutathione to the biologically active 5 mercaptopyrimidine nucleosides. The intermediate 5 thiocyanatopyrimidine nucleosides show significant biological activity, probably as the result of in vivo reduction.
