389612-74-2

Upstream product

• 17754-90-4 4-(Diethylamino)salicylaldehyde 
• 150-13-0 4-amino-benzoic acid 
• 123-30-8 4-amino-phenol 

Downstream Products

• 690982-65-1 Pd(HOC₆H₄NCHC₆H₃NO₂)(HOC₆H₄NCHC₆H₃ON(CH₂CH₃)2) 

Relevant academic research and scientific papers

A novel ratiometric fluorescent probe for sensitive and selective detection of Cu2+ based on Boranil derivatives

A novel ratiometric fluorescent probe 1, consisting of Boranil derivative as the fluorophore and picolinate as the recognition site for Cu2+, was designed and synthesized. 1 was found to display ratiometric response while interacting with Cu2+ by undergoing a Cu2+-promoted hydrolysis of the picolinate moiety for the release of its precursor, 2. We observed that 1 not only showed quick response time (within 10 min), high sensitivity (detection limit of 0.52 μM), and high selectivity for Cu2+ over other metal ions, but also allowed us to detect Cu2+ in a convenient way of observing fluorescence color change under a 365 nm UV lamp using naked eyes. Our study introduced the first ratiometric fluorescent probe for Cu2+ based on Boranil derivative.

Cysteine fluorescence probe as well as preparation method and application thereof

The invention discloses a cysteine fluorescence probe as well as a preparation method and an application thereof. The cysteine fluorescence probe is 4-[7-(diethylamino)-2,2-difluoro benzo[e][1,3,2]oxazaborolidine-3-yl] phenyl acrylate. The preparation met

Novel biothiol fluorescence probe as well as preparation method and application thereof

The invention discloses a novel biothiol fluorescence probe and a preparation method thereof. The novel biothiol fluorescence probe is 4-[7-(diethylamino)-2,2-difluorobenzo[e][1,3,2]oxazaborolidine-3-yl]phenyl-2,4-dinitrobenzene sulfonate. The preparation method comprises steps as follows: (1), 4-(diethylamino) salicylaldehyde and p-aminophenol are subjected to a condensation reaction; (2), 5-diethylamino-2-[[(4-hydroxyphenyl)imine]methyl]-phenol obtained in the step (1) is subjected to a reaction with a boron trifluoride ether solution under the alkaline condition; (3), 4-[7-(diethylamino)-2,2-difluorobenzo[e][1,3,2]oxazaborolidine-3-yl]phenol obtained in the step (2) is subjected to a sulfonylation reaction with 2,4-dinitro benzenesulfonyl chloride, and the novel biothiol fluorescence probe is obtained. The fluorescent probe molecule shows relatively high selectivity and sensitivity on biothiol detection.