389621-24-3

Basic information

• Product Name: (αR,3aS,8bS)-3,3-dimethyl-1-(α-phenylethyl)-1,3a,4,8b-tetrahydro-3H-isoxazolo[3,4-a]pyrrolizine
• CAS NO: 389621-24-3
• Molecular Weight: 282.385
• Mol File: 389621-24-3.mol

Chemical Properties

• CAS DataBase Reference: (αR,3aS,8bS)-3,3-dimethyl-1-(α-phenylethyl)-1,3a,4,8b-tetrahydro-3H-isoxazolo[3,4-a]pyrrolizine(CAS DataBase Reference)
• NIST Chemistry Reference: (αR,3aS,8bS)-3,3-dimethyl-1-(α-phenylethyl)-1,3a,4,8b-tetrahydro-3H-isoxazolo[3,4-a]pyrrolizine(389621-24-3)
• EPA Substance Registry System: (αR,3aS,8bS)-3,3-dimethyl-1-(α-phenylethyl)-1,3a,4,8b-tetrahydro-3H-isoxazolo[3,4-a]pyrrolizine(389621-24-3)

Safety Data

• Hazardous Substances Data: 389621-24-3(Hazardous Substances Data)

Upstream product

• 389621-22-1 C₁₈H₂₂N₂O 
• 2912-98-3 (R)-1-Phenylethylhydroxylamine 
• 110719-45-4 1-(3-methyl-2-butenyl)-pyrrol-2-carbaldehyde 

Downstream Products

• 389621-34-5 (1S,2S,7aS)-1-amino-2,3,5,6,7,7a-hexahydro-2-(1-methylethyl)-1H-pyrrolizine 

Relevant articles and documents

Regiochemical aspects of intramolecular cycloadditions of nitrones derived from N-(2-alkenyl)-2-pyrrolecarbaldehydes. Competitive entries to pyrrolizidine and indolizidine derivatives

Intramolecular cycloadditions of unsaturated nitrones derived from a series of N-(2-alkenyl)-2-pyrrolecarbaldehydes (2) have been systematically studied. A pronounced substituent effect has been observed as far as the competitive formation of fused- and bridged-ring regioisomers are concerned. Further elaboration of the two kinds of cycloadducts has given pyrrolizidine and indolizidine derivatives, respectively.