38965-57-0Relevant academic research and scientific papers
Asymmetric synthesis of α-alkylidene-β-hydroxy-γ- butyrolactones via enantioselective tandem michael-aldol reaction
Lee, Sung Il,Jang, Jin Hee,Hwang, Geum-Sook,Ryu, Do Hyun
, p. 770 - 775 (2013)
A simple and efficient method for the asymmetric synthesis of α-alkylidene-β-hydroxy-γ-butyrolactones and related natural products was developed on the basis of the catalytic asymmetric tandem Michael-aldol reaction and simple transformations. The synthetic utility of this method was illustrated by the facile synthesis of trisubstituted γ-butyrolactone natural products.
