38980-96-0

Basic information

• Product Name: 4-TRIFLUOROMETHYL-BENZAMIDINE HCL
• Synonyms: 4-TRIFLUOROMETHYL-BENZAMIDINE HCL;4-TRIFLUOROMETHYL-BENZAMIDINE HYDROCHLORIDE;4-Trifluoromethylbenzamidinehydrochloridel;4-(Trifluoromethyl)benzenecarboximidamide hydrochloride;4-TrifluoroMethyl-benzanidibe HCL;4-(TrifluoroMethyl)benzenecarboxiMidaMide hydrochloride (1:1)
• CAS NO: 38980-96-0
• Molecular Formula: C₈H₇F₃N₂*ClH
• Molecular Weight: 224.61
• Product Categories: pharmacetical
• Mol File: 38980-96-0.mol
• Article Data: 8

Chemical Properties

• Melting Point: 158-161℃
• Boiling Point: 253.2 °C at 760 mmHg
• Flash Point: 106.9 °C
• Appearance: /
• Density: 1.46g/cm³
• Vapor Pressure: 0.00247mmHg at 25°C
• Refractive Index: 1.62
• Storage Temp.: Inert atmosphere,Room Temperature
• CAS DataBase Reference: 4-TRIFLUOROMETHYL-BENZAMIDINE HCL(CAS DataBase Reference)
• NIST Chemistry Reference: 4-TRIFLUOROMETHYL-BENZAMIDINE HCL(38980-96-0)
• EPA Substance Registry System: 4-TRIFLUOROMETHYL-BENZAMIDINE HCL(38980-96-0)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38-43
• Safety Statements: 26-37/39-36/37
• Hazardous Substances Data: 38980-96-0(Hazardous Substances Data)

Usage

General Description

4-Trifluoromethyl-Benzamidine HCl is a chemical compound that is commonly used as a reagent in chemical synthesis. It is a potent inhibitor of serine proteases and is often used in research and pharmaceutical settings to study proteolytic enzymes. 4-TRIFLUOROMETHYL-BENZAMIDINE HCL has a trifluoromethyl group attached to a benzamidine moiety, which gives it unique chemical properties and makes it useful for specific applications. It is a white to off-white crystalline powder that is stable under standard conditions, and it is typically stored and handled in a dry, well-ventilated area. 4-Trifluoromethyl-Benzamidine HCl is also known by the chemical names N-(4-amidinophenyl)-4,4,4-trifluorobutanamide hydrochloride or Pefabloc SC, and it is important to handle and use this compound with appropriate safety precautions.

InChI:InChI=1/C7H6Cl2N2/c8-4-2-1-3-5(9)6(4)7(10)11/h1-3H,(H3,10,11)

Upstream product

• 455-18-5 4-CF₃C₆H₄CN 
• 56108-08-8 4-Trifluoromethyl-benzimidic acid methyl ester; hydrochloride 
• 22179-86-8 4-(trifluoromethyl)benzamidoxime 

Downstream Products

• 115127-52-1 3-chloro-3-(4-trifluoromethylphenyl)diaziridine 
• 95911-64-1 3-(p-(trifluoromethyl)phenyl)diazirine 
• 851069-61-9 4-methyl-2-(4-trifluoromethyl-phenyl)-pyrimidine-5-carboxylic acid ethyl ester 
• 762286-20-4 methyl 2-(4-(trifluoromethyl)phenyl)imidazole-5-carboxylate 
• 851069-67-5 4-cyclopropyl-2-(4-trifluoromethyl-phenyl)-pyrimidine-5-carboxylic acid ethyl ester 
• 851069-56-2 4-(2-methoxy-ethyl)-2-(4-trifluoromethyl-phenyl)-pyrimidine-5-carboxylic acid ethyl ester 
• 851070-18-3 4-(2-methoxy-ethyl)-6-methyl-2-(4-trifluoromethyl-phenyl)-pyrimidine-5-carboxylic acid methyl ester 
• 466664-93-7 [2-[4-(trifluoromethyl)phenyl]-1H-imidazol-4-yl]methanol 
• 1450790-46-1 2-(4-(trifluoromethyl)phenyl)-7,8-dihydro-3H-thiopyrano[3,2-d]pyrimidin-4(6H)-one 
• 1450790-49-4 2-(4-(trifluoromethyl)phenyl)-5,6-dihydro-3H-pyrano[3,4-d]pyrimidin-4(8H)-one 
• 1285661-67-7 2-(4-(trifluoromethyl)phenyl)-5,6,7,8-tetrahydroquinazolin-4(3H)-one 
• 1450790-48-3 2-(4-(trifluoromethyl)phenyl)-7,8-dihydro-3H-pyrano[4,3-d]pyrimidin-4(5H)-one 
• 1613637-84-5 2,4-bis(4-(trifluoromethyl)phenyl)-1,3,5-triazine 
• 30377-13-0 2-methyl-4,6-di-p-tolyl-1,3,5-triazine 

Relevant articles and documents

Silver-catalyzed [3+2+1] annulation of aryl amidines with benzyl isocyanide

A silver-catalyzed [3+2+1] annulation of amidines with benzyl isocyanide toward 2,4-diaryl-1,3,5-triazines was developed. A variety of symmetrical and unsymmetrical products were obtained in moderate to good yields. This work also features an oxidant-free approach to 2,4-disubstituted triazines.

Preparation of amidines from amidoximes via transfer hydrogenation

Amidoximes are reduced into amidine using triethyl silane and PdCl 2 in acetic acid. Copyright

Thienyloxypyridines and-pyrimidines useful as herbicidal agents

The present invention provides a herbicidal compound of formula I, methods for the preparation thereof and intermediates useful therefor. wherein X and Y are each independently O or S; Z is N or CR4.