39008-28-1

Usage

Uses

Used in Pharmaceutical Industry:
5,6-Diamino-3-methyl-2-methylthio-4(3H)pyrimidinone is used as a synthetic intermediate for the development of various pharmaceutical products. Its unique chemical structure allows it to be a key component in the synthesis of drugs with specific therapeutic applications.
Used in Chemical Synthesis:
In the chemical industry, 5,6-Diamino-3-methyl-2-methylthio-4(3H)pyrimidinone is utilized as a synthetic intermediate for creating a wide range of chemical compounds. Its versatile structure makes it a valuable building block for the development of new materials and products.
Used in Research and Development:
5,6-Diamino-3-methyl-2-methylthio-4(3H)pyrimidinone is also employed in research and development settings, where it is used to study its properties and potential applications in various fields, including pharmaceuticals, materials science, and chemical engineering. Its unique structure and properties make it an interesting subject for scientific investigation and innovation.

InChI:InChI=1/C6H10N4OS/c1-10-5(11)3(7)4(8)9-6(10)12-2/h7-8H2,1-2H3

Upstream product

• 42026-60-8 4-amino-1,6-dihydro-1-methyl-2-methylthio-5-nitroso-6-oxo-pyrimidine 

Downstream Products

• 58947-87-8 3-methyl-1,5-dihydro-pteridine-2,4,6-trione 
• 90350-05-3 3-methyl-2,4,6-trioxo-1,2,3,4,5,6-hexahydro-pteridine-7-carboxylic acid methylamide 
• 1072880-13-7 10-methyl-9-methylthio-6-(4-trifluoromethylphenyl)-6,7,10,12-tetrahydroindeno[1,2-e]pyrimido[4,5-b][1,4]diazepine-5,11-dione 
• 1072880-07-9 10-methyl-9-methylthio-6-(4-chlorophenyl)-6,7,10,12-tetrahydroindeno[1,2-e]pyrimido[4,5-b][1,4]diazepine-5,11-dione 
• 1072880-11-5 10-methyl-9-methylthio-6-(4-methylphenyl)-6,7,10,12-tetrahydroindeno[1,2-e]pyrimido[4,5-b][1,4]diazepine-5,11-dione 
• 1072880-09-1 10-methyl-9-methylthio-6-(4-fluorophenyl)-6,7,10,12-tetrahydroindeno[1,2-e]pyrimido[4,5-b][1,4]diazepine-5,11-dione 
• 1072880-08-0 10-methyl-9-methylthio-6-(4-bromophenyl)-6,7,10,12-tetrahydroindeno[1,2-e]pyrimido[4,5-b][1,4]diazepine-5,11-dione 
• 1072880-12-6 10-methyl-9-methylthio-6-(4-methoxyphenyl)-6,7,10,12-tetrahydroindeno[1,2-e]pyrimido[4,5-b][1,4]diazepine-5,11-dione 
• 1072880-06-8 10-methyl-9-methylthio-6-(4-nitrophenyl)-6,7,10,12-tetrahydroindeno[1,2-e]pyrimido[4,5-b][1,4]diazepine-5,11-dione 
• 1072880-10-4 10-methyl-9-methylthio-6-phenyl-6,7,10,12-tetrahydroindeno[1,2-e]pyrimido[4,5-b][1,4]diazepine-5,11-dione 
• 89181-83-9 1,6-Dihydro-1-methyl-4,5-diamino-6-oxo-pyrimidin 

Relevant academic research and scientific papers

Pteridine nucleotide analogs as fluorescent DNA probes

The invention provides novel pteridine nucleotides which are highly fluorescent under physiological conditions and which may be used in the chemical synthesis of fluorescent oligonucleotidcs. The invention further provides for fluorescent oligonucleotides comprising one or more pteridine nucleotides. In addition the invention provides for pteridine nucleotide triphosphates which may be used as the constituent monomers in DNA amplification procedures.

New Heterocyclic Structures. Thiadiazolopyrimidothiazine and Thiazolothiadiazolopyrimidine

Derivatives of two new molecular structures, namely, 7,8-dihydro-6H,10H-thiadiazolopyrimidothiazin-10-one and 6,7-dihydro-9H-thiazolothiadiazolopyrimidin-9-one, and derivatives of N-substituted sulfamic acid, namely, (8-amino-3,4-dihydro-2H,6H-pyrimidothiazin-6-on-7-yl)sulfamic acid and (7-amino-2,3-dihydro-5H-thiazolopyrimidin-5-on-6-yl)sulfamic acid, were separated out as by-products in the reduction reaction of 8-amino-3,4-dihydro-7-nitroso-2H,6H-pyrimidothiazin-6-one and 7-amino-2,3-dihydro-6-nitroso-5H-thiazolopyrimidin-5-one derivatives, respectively, with sodium hydrosulfide.A mechanism of reaction, which hypothesizes tha action of sodium hydrosulfite in an asymmetric form, is proposed.The results of single-crystal X-ray investigation on 7,8-dihydro-6H,10H-thiadiazolopyrimidothiazin-10-one (R = 0.032 for 863 reflections) and (8-amino-3,4-dihydro-2H,6H-pyrimidothiazin-6-on-7-yl)sulfamic acid, sodium salt (R = 0.028 for 3507 reflections) are reported.