390424-06-3

Upstream product

• 390424-04-1 2-[4-(1-tert-butoxycarbonylamino-3,4-dihydroxy-butyl)-phenyl]-4-(tert-butyl-dimethyl-silanyloxy)-pyrrolidine-1-carboxylic acid tert-butyl ester 
• 390424-01-8 (2R,4R)-4-(tert-Butyl-dimethyl-silanyloxy)-2-{4-[(S)-1-((S)-1-methoxycarbonyl-2-methyl-propylamino)-but-3-enyl]-phenyl}-pyrrolidine-1-carboxylic acid tert-butyl ester 
• 390423-98-0 2-[4-(1-tert-butoxycarbonylamino-but-3-enyl)-phenyl]-4-(tert-butyl-dimethyl-silanyloxy)-pyrrolidine-1-carboxylic acid tert-butyl ester 
• 390424-03-0 (2R,4R)-4-(tert-Butyl-dimethyl-silanyloxy)-2-{4-[(S)-1-((S)-1-hydroxymethyl-2-methyl-propylamino)-but-3-enyl]-phenyl}-pyrrolidine-1-carboxylic acid tert-butyl ester 
• 228267-22-9 (2R,4R)-1-tert-butoxycarbonyl-4-tert-butyldimethylsiloxy-2-(4-formylphenyl)pyrrolidine 
• 24424-99-5 di-tert-butyl dicarbonate 
• 405264-53-1 2-[4-(1-tert-butoxycarbonylamino-3-oxo-propyl)-phenyl]-4-(tert-butyl-dimethyl-silanyloxy)-pyrrolidine-1-carboxylic acid tert-butyl ester 

Downstream Products

• 312297-72-6 (2R,4R)-1-tert-butoxycarbonyl-2-[4-[(S)-1-tert-butoxycarbonylamino-2-carbonylethyl]phenyl]-4-hydroxypyrrolidine 
• 312297-53-3 (2R,4S)-4-acetylthio-1-tert-butoxycarbonyl-2-[4-[(S)-1-tert-butoxycarbonylamino-2-carbamoylethyl]phenyl]pyrrolidine 
• 312297-52-2 (2R,4R)-1-tert-butoxycarbonyl-2-[4-[(S)-1-tert-butoxycarbonylamino-2-carbamoylethyl]phenyl]-4-mesyloxypyrrolidine 

Relevant academic research and scientific papers

Diastereoselective allylation of a chiral imine with allylzinc reagents: Diastereoselective synthesis of a novel broad spectrum carbapenem

Diastereoselective allylation of chiral imine with allyl-metal reagents was applied to prepare β-amino acid derivative as a key intermediate for the synthesis of a novel carbapenem 1. Combination of the allylzinc reagents and chiral imine, which was derived from L-valine methyl ester as a chiral auxiliary afforded a homoallylamine in good yield with excellent diastereoselectivity.