39066-49-4Relevant academic research and scientific papers
Highly selective synthesis of 1-polyfluoroaryl-1,2,3-triazoles via a one-pot three-component reaction
Cao, Liming,Liu, Cuibo,Tang, Xiangyang,Yin, Xuguang,Zhang, Bin
, p. 5033 - 5037 (2014)
A series of 1-polyfluoroaryl-1,2,3-triazoles were synthesized in moderate to good yields by an efficient copper-catalyzed one-pot three-component reaction of polyfluoroarenes, sodium azide, and terminal alkynes. The method involves a polyfluoroarylated azide intermediate produced in situ by the selective CF bond cleavage of polyfluoroarene with sodium azide.
