39069-52-8 Usage
Uses
Used in Pharmaceutical Industry:
GS 39783 is used as a therapeutic agent for the treatment of cocaine addiction. It works by attenuating acute cocaine-induced hyperlocomotion and blocking cocaine-induced Fos induction in the striatal complex, which are key factors in the development of addiction.
Additionally, GS 39783 could potentially be used in other applications related to the modulation of GABAB receptors, such as the treatment of neurological disorders or the development of novel anesthetics. However, further research would be needed to explore these possibilities.
Biological Activity
Novel positive allosteric modulator of GABA B receptor function. Potentiates the effects of GABA on [ 35 S]GTP γ S binding at recombinant and native GABA B receptors (EC 50 values are 2.1 and 3.1 μ M respectively). Decreases cocaine self-administration, blocks the rewarding properties of nicotine and produces anxiolytic-like activity without the side effects associated with baclofen or benzodiazepines.
Check Digit Verification of cas no
The CAS Registry Mumber 39069-52-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,9,0,6 and 9 respectively; the second part has 2 digits, 5 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 39069-52:
(7*3)+(6*9)+(5*0)+(4*6)+(3*9)+(2*5)+(1*2)=138
138 % 10 = 8
So 39069-52-8 is a valid CAS Registry Number.
