39087-92-8

Upstream product

• 446-52-6 2-Fluorobenzaldehyde 
• 98-95-3 nitrobenzene 
• 446-51-5 2-fluorobenzyl alcohol 
• 62-53-3 aniline 

Downstream Products

• 148004-79-9 1-fluoro-2-((4-fluorophenyl)ethynyl)benzene 
• 1024218-25-4 C₁₆H₁₆FN 
• 940362-32-3 N-(2-fluorobenzyl)benzenamine 
• 1354725-53-3 C₁₈H₂₀FN 
• 1245731-13-8 C₆H₅SC₆H₄NHC₆H₄CH₂NHC₆H₅ 
• 1231728-61-2 N-[1-(2-fluorophenyl)-3,3,3,2,2-pentafluoropropyl]aniline 
• 1146747-23-0 (2-fluoro-phenyl)-phenylamino-acetic acid 
• 148004-82-4 2,4'-Diphenoxytolane 

Relevant academic research and scientific papers

General and selective reductive amination of carbonyl compounds using a core-shell structured Co3O4/NGr@C catalyst

The application of heterogenized non-noble metal-based catalysts in selective catalytic hydrogenation processes is still challenging. In this respect, the preparation of a well-defined cobalt-based catalyst was investigated by immobilization of the corresponding cobalt(ii)-phenanthroline-chelate on Vulcan XC72R carbon powder. The formed core-shell structured cobalt/cobalt oxide nanocomposites are encapsulated by nitrogen-enriched graphene layers. This promising cheap heterogeneous catalyst allows for an efficient domino reductive amination of carbonyl compounds with nitroarenes. This journal is

Synthesis of organoaluminum chalcogenides and their applications in Lewis acid catalysis

Two chalcogenide bridged bi-aluminum compounds [LAl(NMe3)(μ-S)Al(NMe3)L] (1) and [LAl(NMe3)(μ-Se)Al(NMe3)L] (2) were synthesized by reacting LAlH(NMe3) (L = 4-methylbenzylidene-o-aminothiophenol) with

Mild and efficient synthesis of secondary aromatic amines by one-pot stepwise reductive amination of arylaldehydes with nitroarenes promoted by reusable nickel nanoparticles

The one-pot stepwise reductive amination of arylaldehydes with nitroarenes is described, using reusable nickel nanoparticles (Ni-pol) as catalyst and NaBH4 as mild, inexpensive, and safe reducing agent. The proposed catalytic system holds several advantages such as the use of a non-precious and earth-abundant metal, the facile separation of the catalyst from the reaction mixture by centrifugation, excellent stability towards air and moisture, very mild reaction conditions, good recyclability, broad substrate scope with good to excellent yields, and easy scalability (up to 1.0 g). FESEM analyses indicate that the active species are cubic nanocrystals of Ni in the average cross section value of 35 nm with a quite narrow (25–45 nm) and monomodal distribution, which becomes bimodal with the recycling reactions but without agglomeration.

Activated Carbon Supported Ruthenium Nanoparticles Catalyzed Synthesis of Imines from Aerobic Oxidation of Alcohols with Amines

Abstract: Imines were synthesized from the cross-coupling of alcohols with amines catalyzed by activated carbon (AC) supported ruthenium nanoparticles under atmospheric molecular oxygen without aid of any additives. The readily prepared catalyst 5%Ru/AC showed good to excellent (yield > 90%) performances in the reaction of aromatic and heterocyclic alcohols with various amines, such as aromatic, aliphatic and heterocyclic amines. This protocol is simple, efficient, and environmentally friendly, and the catalyst can be easily recovered without major ruthenium loss. Graphical Abstract: Imines were synthesized from the cross-coupling of alcohols with amines catalyzed by activated carbon (AC) supported ruthenium nanoparticles under atmospheric molecular oxygen without aid of any additives. This protocol is simple, efficient, and environment friendly, and the readily prepared catalyst 5%Ru/AC showed good to excellent performances in the reaction of aromatic and heterocyclic alcohols with various amines, such as aromatic, and aliphatic amines. [Figure not available: see fulltext.]

Synthesis of [LAl(μ-S)2AlL] (L?=?HC(CMeNAr)2, Ar?=?2,6-Et2C6H3) with the insertion of sulfur into the Al–H bonds of LAlH2 and its application in catalysis

Two aluminum complexes [LAl(μ-S)2AlL] (1) and [LAl(SeH)2] (2) were synthesized in good yield by reacting one equivalent of LAlH2 (L?=?HC(CMeNAr)2, Ar?=?2,6-Et2C6H3) with one equivalent of S and with two equivalents of Se without any catalysts, respectively. Complexes 1 and 2 have been characterized by 1H and 13C NMR, elemental analyses, and single crystal X-ray structural analysis. Furthermore, the good catalytic activity of 1 as bimetallic Lewis acid catalyst for the addition reaction of TMSCN to aldehydes and aldimine condensation reactions, respectively, were investigated.

An Efficient Lewis Acid Catalyzed Povarov Reaction for the One-Pot Stereocontrolled Synthesis of Polyfunctionalized Tetrahydroquinolines

An easy and efficient synthetic methodology for the one-pot stereocontrolled synthesis of tetrahydroquinolines through Lewis acid activated Povarov reaction is described. The protocol takes advantage of the very cheap, easy to handle, and environmentally

Reductive Umpolung of Carbonyl Derivatives with Visible-Light Photoredox Catalysis: Direct Access to Vicinal Diamines and Amino Alcohols via α-Amino Radicals and Ketyl Radicals

Visible-light-mediated photoredox-catalyzed aldimine-aniline and aldehyde-aniline couplings have been realized. The reductive single electron transfer (SET) umpolung of various carbonyl derivatives enabled the generation of intermediary ketyl and α-amino radical anions, which were utilized for the synthesis of unsymmetrically substituted 1,2-diamines and amino alcohols. Anilines can be coupled with aldimines or aldehydes in a visible-light-mediated photoredox-catalyzed process. Reductive single electron transfer (SET) umpolung of the carbonyl derivatives leads to the generation of intermediary ketyl and α-amino radical anions, which were used for the synthesis of unsymmetrically substituted 1,2-diamines and amino alcohols.

Silver-catalyzed alkyne activation: The surprising ligand effect

An unexpected ligand effect was discovered in the silver(I)-catalyzed alkyne activation. For both aldehyde-alkyne-amine (A3) condensation and intermolecular alkyne hydroamination, the type B complex (P:Ag=1:1) effectively promoted the reaction, while no reaction occurred with either no ligand or excess ligands under the identical conditions.

Magnesium catalysis of imine hydroboration

The β-diketiminato magnesium alkyl complex [LMgnBu] (L=CH{CMe(NDipp)}2, Dipp=diisopropylphenyl) is shown to be a highly effective precatalyst for the hydroboration of alkyl and aryl substituted aldimines and ketimines with pinacol borane (HBpin). Catalysis is proposed to occur through a sequence of Mg-N/B-H metathesis and rate-determining Mg-H/N=C insertion steps, a proposal strongly supported by stoichiometric studies and kinetic analysis. The reactions are observed to proceed through the intermediacy of well-defined magnesium amides, two examples of which have been isolated and structurally characterized. Mechanistic investigations suggest that the catalytic rate-determining process occurs at an isolated magnesium center and requires the presence of two molecules of the imine substrate for effective turnover. This latter observation is rationalized as a requirement for the secondary substrate molecule to displace HBpin from the coordination sphere of the catalytic magnesium center.

Syntheses, reactions, and ethylene polymerization of titanium complexes with [N,N,S] ligands

Tridentate dianionic arylsulfide free ligands [ArNHCH2C 6H4NHC6H4-2-SPh] (Ar = Ph (3a); Ar = 2,4,6-trimethylphenyl (3b); Ar = 2,6-diisopropylphenyl (3c)) have been prepared by reduction of the corresp