391-10-6

Usage

Molecular structure

The compound has an isoindole-1,3-dione core, a trifluoromethylphenyl group, and a ketone functional group.

Molecular weight

374.30 g/mol

Appearance

The compound is likely a solid with a specific color that is not provided in the material.

Solubility

The compound's solubility is not provided in the material, but it may vary depending on the solvent used.

Potential applications

The compound is commonly used in medicinal chemistry and pharmaceutical research due to its potential as a bioactive molecule. It may be investigated for its potential as a drug candidate for various therapeutic applications, including anti-inflammatory, analgesic, or antimicrobial properties.

Unique structure and chemical properties

The compound's unique structure and chemical properties make it a subject of interest for further research and development in the pharmaceutical industry.

Upstream product

• 383-53-9 2-bromo-1-[4-(trifluoromethyl)phenyl]ethanone 
• 1074-82-4 potassium phtalimide 
• 95727-89-2 4-(trifluoromethyl)phenyl chloromethylketone 
• 709-63-7 1-(4-trifluoromethylphenyl)ethanone 

Downstream Products

• 1607823-33-5 C₂₇H₂₆F₃NO₆S₂ 
• 1607823-28-8 S-1-(1,3-dioxoisoindolin-2-yl)-2-(4-(trifluoromethyl)phenyl)-2-oxoethyl O-ethyl carbonodithioate 
• 1607823-24-4 C₁₇H₉BrF₃NO₃ 
• 771582-55-9 2-amino-1-[4-(trifluoromethyl)phenyl]ethanone 
• 1580-99-0 N-(4-trifluoromethyl-phenacyl)-phthalamic acid 

Relevant academic research and scientific papers

Convergent routes to substituted naphthylamides

Practical, convergent routes to variously substituted 1- and 2-naphthylamides have been developed. They exploit the ability of xanthates to undergo both intermolecular radical additions to vinyl pivalate and intramolecular radical cyclisations to aromatic

New Anticancer Agents: Synthesis of 1,2-Dihydropyridopyrizines (1-Deaza-7,8-dihydropteridines)

Reaction of α-aminoacetophenone oximes (2) with ethyl 6-amino-4-chloro-5-nitropyridine-2-carbamate (1) gave ethyl 6-amino-5-nitro-4-pyridine-2-carbamate oximes (3), which were hydrolyzed under acidic conditions to give the corresponding ketones (4).Related pyridines substituted with keto side chain were prepared from 1 and 1,3-diaminopropanone oximes and by oxidation of the side-chain hydroxy group of ethyl 6-amino-4-amino>-5-nitropyridine-7-carbamates (6).Catalytic hydrogenation of the nitro group of 4 over Raney nickel in a large volume of ethanol gave the 1-deaza-7,8-dihydropteridines (7).Several of the oximes 3 were successfully hydrogenated to give 7 directly.The resulting 1-deaza-7,8-dihydropteridines showed potent cytotoxicity against cultured L1210 cells and significant anticancer activity against lymphocytic leukemia P-388 in mice.THese biological activities are attributed to the accumulation of cells at mitosis.