39124-16-8

Basic information

• Product Name: 4-Aminotetrahydrothiopyran-4-carboxylic acid
• Synonyms: 4-Amino-4-carboxyltetrahydrothiapyran
• CAS NO: 39124-16-8
• Molecular Formula: C₆H₁₁NO₂S
• Molecular Weight: 161.22
• Product Categories: pharmacetical;Carboxylic Acids;Ring Systems
• Mol File: 39124-16-8.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 334.7°Cat760mmHg
• Flash Point: 156.2°C
• Appearance: /
• Density: 1.298g/cm³
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 4-Aminotetrahydrothiopyran-4-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Aminotetrahydrothiopyran-4-carboxylic acid(39124-16-8)
• EPA Substance Registry System: 4-Aminotetrahydrothiopyran-4-carboxylic acid(39124-16-8)

Safety Data

• Hazardous Substances Data: 39124-16-8(Hazardous Substances Data)

Usage

Description

4-Aminotetrahydrothiopyran-4-carboxylic acid is a heterocyclic chemical compound characterized by a tetrahydrothiopyran ring, an amino group, and a carboxylic acid functional group. It is widely utilized in organic synthesis and pharmaceutical research due to its potential therapeutic properties, including anti-inflammatory and antibacterial effects. The unique structure of this compound renders it a valuable asset in the development of pharmaceutical drugs and bioactive compounds.

Uses

Used in Pharmaceutical Research:
4-Aminotetrahydrothiopyran-4-carboxylic acid is used as a building block in the synthesis of various pharmaceutical drugs and bioactive compounds, contributing to the development of new therapeutic agents.
Used in Organic Synthesis:
4-Aminotetrahydrothiopyran-4-carboxylic acid serves as an important intermediate in organic synthesis, facilitating the creation of complex organic molecules for a range of applications.
Used in Medicinal Research:
4-Aminotetrahydrothiopyran-4-carboxylic acid is used as a research tool in medicinal chemistry to explore its potential therapeutic properties, such as its anti-inflammatory and antibacterial effects, which could lead to the discovery of novel treatments for various diseases and conditions.
Used in Drug Development:
In the pharmaceutical industry, 4-Aminotetrahydrothiopyran-4-carboxylic acid is utilized in drug development processes, where its unique structure aids in the design and synthesis of new drugs with improved efficacy and safety profiles.

Upstream product

• 1072-72-6 Tetrahydrothiopyran-4-one 
• 773837-37-9 sodium cyanide 
• 50289-20-8 4-amino-tetrahydro-2H-thiopyran-4-carbonitrile 
• 39124-15-7 4-thio-1H-tetrahydropyranespiro-5'-hydantoin 

Downstream Products

• 39974-69-1 C₁₄H₁₇NO₄S 
• 594872-59-0 N-[4-(3,5-dimethyl-benzoyl)-tetrahydro-thiopyran-4-yl]-3-methoxy-2-methyl-benzamide 

Relevant articles and documents

Extended diethylglycine homopeptides formed by desulfurization of their tetrahydrothiopyran analogues

Diethylglycine (Deg) homopeptides adopt the rare 2.05-helical conformation, the longest three-dimensional structure that a peptide of a given sequence can adopt. Despite this unique conformational feature, Deg is rarely used in peptide design b

Method for the synthesis of compounds of formula 1 and derivatives thereof

Mono-substituted and di-substituted alpha-amino acids and derivatives thereof, substituted at the alpha positon with one (mono-) or two (di-) substituents (R2 and/or R3) as shown in Formula 1: N(R4R5)C(R2R3)CO(OR1).

ARYLSUFONAMIDO-SUBSTITUTED HYDROXAMIC ACIDS

The invention relates to a method of inhibiting metalloellastase activity, of inhibiting the degradation of elastin, or of treating macrophage metalloelastase dependent conditions in mammals which comprises administering to a mammal in need thereof an effective macrophage metalloelastase inhibiting amount of a compound of formula I STR1 wherein Ar, R, R 1 and R. sub.2 have meanings as defined, or of a pharmaceutically acceptable prodrug derivative thereof, or of a pharmaceutically acceptable salt thereof, or of pharmaceutical compositions comprising a said compound.