39126-59-5Relevant academic research and scientific papers
Synthesis and antimicrobial evaluation of 2β-chloromethyl-6β-carbamoylmethyl-penam-1,1-dioxide-3-carboxylic acid
Gaviraghi,Perboni,Tamburini,Xerri,Salvatori,Spadoni,Tarzia
, p. 535 - 538 (2007/10/03)
A new 2β-Chloromethyl-6β-carbamoylmethyl-penam-1,1-dioxide-3-carboxylic acid was synthesised and evaluated for its antimicrobial and β-lactamase inhibitory activity. The compound was found to be inactive.
Synthesis of 6-Vinylidenepenams
Buynak, John D.,Borate, H. B.,Lamb, Grady W.,Khasnis, Dipti D.,Husting, Chad,et al.
, p. 1325 - 1335 (2007/10/02)
The preparation of unique penicillin derivatives containing an exocyclic allene at the 6 position (6-vinylidenepenams) is described.The synthetic scheme utilizes 6-oxopenicillinates as intermediates which stereospecifically add acetylide anions forming pr
A new synthesis of 6-oxopenicillanates by ozonolysis of 6-diazopenicillanates
Ursini,Pellicciari,Tamburini,Carlesso,Gaviraghi
, p. 363 - 364 (2007/10/02)
In this paper we describe a convenient new procedure for preparing 6-oxopenicillanates, via ozonization of the corresponding 6-diazo derivatives.
Method of producing oxo-containing azetidinone compounds
-
, (2008/06/13)
This invention relates to a novel method of producing oxo-containing azetidinone compounds, or salts thereof, or hydrates thereof, said compounds having utility as antimicrobial agents and as intermediates for the synthesis of other azetidinone compounds having antimicrobial activity.
An Efficient Synthesis of 6-Oxopenicillanic and 7-Oxocephalosporanic Acid Derivatives
Hagiwara, Daijiro,Sawada, Kozo,Ohnami, Tetsuo,Aratani, Matsuhiko,Hashimoto, Masashi
, p. 578 - 579 (2007/10/02)
Trifluoromethanesulphonation of benzyl 6-aminopenicillanate (3) and the 7-aminocephalosporanates (7a-c) with (CF3SO2)2O gave the bis(trifluoromethylsulphonate) derivatives (5) and (8a-c), which were then converted into the imines (6) and (9a-c) by treatme
Carbon and oxygen analogs of penicillin
-
, (2008/06/13)
In accordance with this invention, it has been found that carbon and oxygen analogs of 6β-aminopenicillanic acid and biologically active derivatives thereof can be formed from esters of 6-oxopenicillanic acid. For example, 6β-phenoxyacetoxypenicillanic ac
Process for preparing 7-oxo cephalosporins and 6-oxo penicillins
-
, (2008/06/13)
A process for preparing 7-oxo cephalosporins and 6-oxo penicillins by reaction of a 7-amino cephalosporin or 6-amino penicillin with a carbonyl-containing oxidizing agent is disclosed.
