39128-27-3

Upstream product

• 106-49-0 p-toluidine 
• 1122-91-4 4-bromo-benzaldehyde 
• 873-75-6 4-bromobenzenemethanol 
• 127598-63-4 N-(4-bromobenzyl)-4-methylaniline 

Downstream Products

• 127598-63-4 N-(4-bromobenzyl)-4-methylaniline 
• 143874-33-3 (3R,4S)-4-(4-Bromo-phenyl)-3-phenyl-1-p-tolyl-azetidin-2-one 
• 140424-48-2 2-(4-Bromo-phenyl)-4-hydroxy-5-oxo-1-p-tolyl-2,5-dihydro-1H-pyrrole-3-carboxylic acid tert-butyl ester 
• 1104927-25-4 methyl 2-(9-anthrylmethoxy)-3-(-p-tolylamino)-3-(4-bromophenyl)-2-phenylpropanoate 
• 1336883-82-9 2,2-dichloro-3-(4-chlorophenyl)-1-(4-methylphenyl)aziridine 
• 1333412-75-1 4-methyl-N-[1-(4-bromophenyl)but-3-enyl]aniline 

Relevant academic research and scientific papers

Synthesis and characterization of tetrachloro-1,3-oxazepine derivatives and evaluation of their biological activities

6,7,8,9-Tetrachloro[1,3]oxazepine-1,5-dione derivatives 1b-10b have been synthesized by reacting Schiff bases 1a-10a with tetrachlorophthalic anhydride (TCPA) under (2 + 5 → 7) cycloaddition reaction conditons. All reactions had been monitored using TLC.

Systematic studies on mechanochemical synthesis: Schiff bases from solid aromatic primary amines and aldehydes

A versatile and robust mechanochemical route to Aldehyde–Schiff base conversions has been established for a broad range of aldehydes via a simple cogrinding in mortar with a pestle under a solvent-free, as well as solvent-assisted, environment. The extent

Indium-assisted aluminium-based stereoselective allylation of prostereogenic α,α-disubstituted cycloalkanones and imines

The use of a catalytic amount of InCl3in combination with Al0for the allylation of a variety of prostereogenic α,α-disubstituted (hindered) cycloalkanones, 1,2-dione-based systems and various imino systems (CN functional groups) is reported. The stereoselective InCl3-catalyzed Al-based allylation of various 2-substituted-2-carbethoxycycloalkanones gave the corresponding products with moderate to excellent diastereoselectivity. The allylation and propargylation of imines including α-imino esters using a catalytic amount of InCl3in combination with Al0gave the corresponding allylated and propargylated compounds in moderate to good yields. If γ-substituted allylic halides were added to imino compounds, low to very good diastereoselectivity was obtained. The allylation of chiral N-tert-butylsulfinyl imine systems gave the corresponding products in moderate yields with good to excellent diastereoselectivity. This journal is

Dehydrogenation and oxidative coupling of alcohol and amines catalyzed by organosilicon-supported TiO2@PMHSIPN

The catalytic dehydrogenation and tandem transformation of aromatic alcohols, including oxidative coupling of alcohols and amines, were achieved successfully using a catalytic amount of organosilicon-supported titania (TiO2@PMHSIPN), which enables the efficient synthesis of aromatic aldehydes, imines, and benzimidazoles in good to excellent yields. This journal is the Partner Organisations 2014.

Aerobic dehydrogenative imination in complete aqueous media catalyzed by poly(aniline sulfonic acid)/gold nanoparticles

Dehydrogenative imination in aqueous media was achieved using poly(2-methoxyaniline-5-sulfonic acid) (PMAS)/gold nanoparticles, where PMAS worked as a redox mediator.

Fast and efficient reductive amination of aldehydes by NaBH 4/B(OH)3 and NaBH4/Al(OH)3

Reductive amination a variety of aldehydes and anilines to their corresponding secondary amines were carried out with NaBH4/B(OH) 3 and NaBH4/Al(OH)3 as new reducing systems in CH3CN at room temperature in high to excellent yields of products (90-96%).

GREEN SYNTHESIS OF ARYL ALDIMINES USING ETHYL LACTATE

The present invention relates to a method for preparing aryl aldimines. In particular, the present invention relates to methods of preparing aryl aldimines that uses environmentally friendly solvent systems.

Selectivity control in enantioselective four-component reactions of aryl diazoacetates with alcohols, aldehydes and amines: An efficient approach to synthesizing chiral β-amino-α-hydroxyesters

Enantioselective four-component reactions of aryl diazoacetates with alcohols, aldehydes and amines catalyzed cooperatively by a rhodium complex and a chiral Bronsted acid produce β-amino-α-hydroxyl acid derivatives in a single step with excellent control

Solid-state radical reactions of 1,3-cyclohexanediones with in situ generated imines mediated by manganese(III) acetate under mechanical milling conditions

Under solid-state conditions, manganese(III) acetate-mediated radical reactions of 1,3-cyclohexanedione and 5,5-dimethyl-1,3-cyclohexanedione with in situ generated imines proceeded efficiently by mechanical milling at room temperature and good to excelle

Understanding solid/solid organic reactions

The concept of an organic reaction between two macroscopic solid particles is investigated. Thus, we study several reactions that have been recently reported to proceed "in the solid phase" and clearly show that, in most cases, grinding the two solid reactants together results in the formation of a liquid phase. This is true both for catalytic transformations (e.g., aldol condensations and oligomerization of benzylic compounds) and for noncatalytic reactions (Baeyer - Villiger oxidations, oxidative coupling of naphthols using iron chloride, condensation of amines and aldehydes to form azomethines, homo-etherification of benzylic alcohols using p-toluenesulfonic acid, and nuclear aromatic bromination with NBS). This liquefaction implies the existence of a eutectic mixture with Tfusion below ambient temperature (although both reagents have higher than ambient melting points). In cases where heating is required, it is again clear that a phase change (from solid to liquid) occurs, explaining the observed reaction kinetics. On the basis of 19 experimental examples, we discuss the possibility of solid-phase organic reactions and the implications of these findings to the reaction between two solid reagents. A general description of such reactive systems is proposed, based on a consideration of the potential for eutectic (or peritectic) formation between the constituents of the liquid phases that arise during the process of mechanical mixing of the solid reagents and products.