39137-60-5Relevant academic research and scientific papers
2,6,7-Trithiabicyclo[2.2.2]octanes as promising photolabile tags for combinatorial encoding
Valiulin, Roman A.,Kutateladze, Andrei G.
, p. 335 - 338 (2008/09/17)
(Chemical Equation Presented) The adducts of trithiabicyclo[2.2.2]octane (TTBO) and carbonyl compounds undergo efficient photoinduced fragmentation with quantum yields comparable to that of dithiane adducts. The effect of the third sulfur on the stability of the respective radical cations and radicals is examined computationally and experimentally in a laser flash photolysis study. A straightforward synthetic approach to a variety of 4-substituted trithiabicyclo[2.2.2]octanes from 3-bromo-2,2-bis-(bromomethyl)propanol is developed, making a diverse set of mass-differentiated photolabile tags readily available for combinatorial encoding.
