39153-73-6Relevant academic research and scientific papers
A 2, 4, 5 - trifluoro -3 - chlorobenzoic acid preparation method
-
Paragraph 0016; 0022-0027, (2019/02/13)
The invention discloses a 2, 4, 5 - trifluoro - 3 - chlorobenzoic acid preparation method, which belongs to the chemical pharmaceutical intermediates preparation method technical field, the use of 1, 2, 4, - trifluorobenzene as raw materials, by nitration, chloro, re-nitration, reduction, diazotization, cyanide Sandmeyer reaction and hydrolysis reaction for preparing 2, 4, 5 - trifluoro - 3 - chlorobenzoic acid. The method of the invention, the raw materials using relatively inexpensive and easy to obtain, the process route is mature, the operation is simple, high yield, and has high industrial value.
